TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T92424	Integrin alpha-V/beta-5	B1FEL6	(2S)-3-[[2-[(3R,5S)-1-(3,3-Dimethylbutanoyl)-5-[(pyridin-2-ylamino)methyl]pyrrolidin-3-yl]oxyacetyl]amino]-2-[(2,4,6-trimethylbenzoyl)amino]propanoic acid	Investigative	11613998	C31H43N5O6	581.7	CC1=CC(=C(C(=C1)C)C(=O)N[C@@H](CNC(=O)CO[C@@H]2C[C@H](N(C2)C(=O)CC(C)(C)C)CNC3=CC=CC=N3)C(=O)O)C	IC50 ~ 50000 nM	Poor binder
T92424	Integrin alpha-V/beta-5	B85FRU	(2S)-2-[[2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]butanedioic acid	Investigative	90645591	C21H31N7O7	493.5	C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)O)N	IC50 = 80000 nM	Poor binder
T92424	Integrin alpha-V/beta-5	BPEW05	(2S)-3-[[2-[(3S,5R)-1-(3,3-Dimethylbutanoyl)-5-[(pyridin-2-ylamino)methyl]pyrrolidin-3-yl]oxyacetyl]amino]-2-[(2,4,6-trimethylbenzoyl)amino]propanoic acid	Investigative	46226894	C31H43N5O6	581.7	CC1=CC(=C(C(=C1)C)C(=O)N[C@@H](CNC(=O)CO[C@H]2C[C@@H](N(C2)C(=O)CC(C)(C)C)CNC3=CC=CC=N3)C(=O)O)C	IC50 = 90700 nM	Poor binder
T92424	Integrin alpha-V/beta-5	BWD4J9	Arginyl-glycyl-aspartyl-phenylalanine	Investigative	3080994	C21H31N7O7	493.5	C1=CC=C(C=C1)C[C@@H](C(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCN=C(N)N)N	IC50 = 92000 nM	Poor binder