TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T95605	Neurotensin receptor type 2	B0XO2R	2-Cyclobutyl-6-methoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	53245521	C24H28N4O2	404.5	COC1=CC2=C(C=C1)N=C(N=C2N3CCN(CC3)C4=CC=CC=C4OC)C5CCC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B14AFB	6-Ethoxy-7-methoxy-4-[4-(3-methoxyphenyl)piperazin-1-yl]-2-phenylquinazoline	Investigative	73349346	C28H30N4O3	470.6	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC(=CC=C5)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B2OLP8	2-Ethyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline	Investigative	56593293	C23H28N4O3	408.5	CCC1=NC2=CC(=C(C=C2C(=N1)N3CCN(CC3)C4=CC=CC=C4OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B3JG9B	4-[4-(2-Fluorophenyl)piperazin-1-yl]-6,7-dimethoxy-2-phenylquinazoline	Investigative	1920221	C26H25FN4O2	444.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=CC=C5F)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B46JZL	4-[4-(2-Chlorophenyl)piperazin-1-yl]-2-cyclopropyl-6,7-dimethoxyquinazoline	Investigative	56593272	C23H25ClN4O2	424.9	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CC3)N4CCN(CC4)C5=CC=CC=C5Cl)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B4P0QT	[4-(2-Cyclopropyl-6,7-dimethoxyquinazolin-4-yl)piperazin-1-yl]-phenylmethanone	Investigative	56593289	C24H26N4O3	418.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CC3)N4CCN(CC4)C(=O)C5=CC=CC=C5)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B52XPZ	2-Cyclobutyl-4-[4-(2-fluorophenyl)piperazin-1-yl]-6,7-dimethoxyquinazoline	Investigative	52914822	C24H27FN4O2	422.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CCC3)N4CCN(CC4)C5=CC=CC=C5F)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B5HT7G	6,7-Dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]quinazoline	Investigative	56593281	C34H42N6O4	598.7	COC1=CC=CC=C1N2CCN(CC2)CCC3=NC4=CC(=C(C=C4C(=N3)N5CCN(CC5)C6=CC=CC=C6OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B5ZDI8	2-Cyclopropyl-6,7-dimethoxy-4-piperazin-1-ylquinazoline	Investigative	56593292	C17H22N4O2	314.4	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CC3)N4CCNCC4)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B60AFQ	6,7-Dimethoxy-2-phenyl-4-(4-phenylpiperazin-1-yl)quinazoline	Investigative	1951822	C26H26N4O2	426.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=CC=C5)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B6FTO3	6-Cyclobutyl-8-[4-(2-methoxyphenyl)piperazin-1-yl]-[1,3]dioxolo[4,5-g]quinazoline	Investigative	53245574	C24H26N4O3	418.5	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC5=C(C=C43)OCO5)C6CCC6	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B6FYT4	2-Cyclopropyl-6,7-dimethoxy-4-[4-[(4-methylphenyl)methyl]piperazin-1-yl]quinazoline	Investigative	56593291	C25H30N4O2	418.5	CC1=CC=C(C=C1)CN2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B6J9AN	4-[4-(4-Fluorophenyl)piperazin-1-yl]-6,7-dimethoxy-2-phenylquinazoline	Investigative	1941471	C26H25FN4O2	444.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=C(C=C5)F)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B6SU7A	2-Cyclobutyl-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	53245626	C23H26N4O	374.5	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC=CC=C43)C5CCC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B73MER	2-Cyclopropyl-4-[4-(2-ethoxyphenyl)piperazin-1-yl]-6,7-dimethoxyquinazoline	Investigative	56593290	C25H30N4O3	434.5	CCOC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B82WNO	1-(2-Cyclopropyl-6,7-dimethoxyquinazolin-4-yl)-4-(phenylsulfonyl)piperazine	Investigative	56593283	C23H26N4O4S	454.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CC3)N4CCN(CC4)S(=O)(=O)C5=CC=CC=C5)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B8JEF7	2-Cyclopropyl-6,7-dimethoxy-4-(4-(2-methoxyphenyl)piperazin-1-yl)quinazoline	Investigative	53245590	C24H28N4O3	420.5	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B8SNV3	6,7-Dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-(2-methylpropyl)quinazoline	Investigative	56593282	C25H32N4O3	436.5	CC(C)CC1=NC2=CC(=C(C=C2C(=N1)N3CCN(CC3)C4=CC=CC=C4OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B90XGK	2-Ethenyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	56593273	C23H26N4O3	406.5	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C=C	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B9R1XN	4-[4-(2,4-Dimethoxyphenyl)piperazin-1-yl]-6-ethoxy-7-methoxy-2-phenylquinazoline	Investigative	73350917	C29H32N4O4	500.6	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=C(C=C(C=C5)OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	B9W0TI	6-Ethoxy-7-methoxy-4-[4-(2-nitrophenyl)piperazin-1-yl]-2-phenylquinazoline	Investigative	73352405	C27H27N5O4	485.5	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=CC=C5[N+](=O)[O-])OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BB21CE	2-Cyclobutyl-6,7-dimethoxy-4-[4-(2-methylphenyl)piperazin-1-yl]quinazoline	Investigative	51035373	C25H30N4O2	418.5	CC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CCC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BD07IT	6,7-Dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	10339735	C21H24N4O3	380.4	COC1=CC=CC=C1N2CCN(CC2)C3=NC=NC4=CC(=C(C=C43)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BG3JE0	2-Benzyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	53245615	C28H30N4O3	470.6	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)CC5=CC=CC=C5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BGMZ36	2-Cyclobutyl-6,7-dimethoxy-4-(4-phenylpiperazin-1-yl)quinazoline	Investigative	51035368	C24H28N4O2	404.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CCC3)N4CCN(CC4)C5=CC=CC=C5)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BGW52R	6-Ethoxy-7-methoxy-4-[4-(4-methoxyphenyl)piperazin-1-yl]-2-phenylquinazoline	Investigative	73355398	C28H30N4O3	470.6	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=C(C=C5)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BH9UF3	6-Ethoxy-7-methoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylquinazoline	Investigative	73353870	C28H30N4O3	470.6	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=CC=C5OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BJY69G	[4-(2-Cyclopropyl-6,7-dimethoxyquinazolin-4-yl)piperazin-1-yl]-(2-methoxyphenyl)methanone	Investigative	56593279	C25H28N4O4	448.5	COC1=CC=CC=C1C(=O)N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BK7B2G	4-[4-(2-Chlorophenyl)piperazin-1-yl]-6,7-dimethoxy-2-phenylquinazoline	Investigative	73347807	C26H25ClN4O2	461	COC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=CC=C5Cl)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BL15RM	2-Cyclobutyl-7-methoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	53245542	C24H28N4O2	404.5	COC1=CC2=C(C=C1)C(=NC(=N2)C3CCC3)N4CCN(CC4)C5=CC=CC=C5OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BL6FD5	2-Cyclobutyl-6,7-dimethoxy-4-[4-(2-methoxyphenyl)-1-piperazinyl]quinazoline	Investigative	1230852	C25H30N4O3	434.5	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CCC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BLY20R	2-[6,7-Dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazolin-2-yl]-N,N-dimethylethanamine	Investigative	56593274	C25H33N5O3	451.6	CN(C)CCC1=NC2=CC(=C(C=C2C(=N1)N3CCN(CC3)C4=CC=CC=C4OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BM7LO3	2-Cyclobutyl-6,7-dimethoxy-4-(4-pyridin-2-ylpiperazin-1-yl)quinazoline	Investigative	1230851	C23H27N5O2	405.5	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CCC3)N4CCN(CC4)C5=CC=CC=N5)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BNJW48	(2S)-2-[[1-(7-Chloroquinolin-4-yl)-2-(2,6-dimethoxyphenyl)imidazole-4-carbonyl]amino]-4-methylpentanoic acid	Investigative	49837912	C27H27ClN4O5	523	CC(C)C[C@@H](C(=O)O)NC(=O)C1=CN(C(=N1)C2=C(C=CC=C2OC)OC)C3=C4C=CC(=CC4=NC=C3)Cl	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BNX0T6	6,7-Dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-propylquinazoline	Investigative	54758538	C24H30N4O3	422.5	CCCC1=NC2=CC(=C(C=C2C(=N1)N3CCN(CC3)C4=CC=CC=C4OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BR3L0P	4-[4-(2,6-Dimethylphenyl)piperazin-1-yl]-6-ethoxy-7-methoxy-2-phenylquinazoline	Investigative	73356947	C29H32N4O2	468.6	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=C(C=CC=C5C)C)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BSCH20	2-Cyclopropyl-6-methoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	56593278	C23H26N4O2	390.5	COC1=CC2=C(C=C1)N=C(N=C2N3CCN(CC3)C4=CC=CC=C4OC)C5CC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BT6FJ3	4-[4-(2-Chlorophenyl)piperazin-1-yl]-2-cyclobutyl-6,7-dimethoxyquinazoline	Investigative	52914819	C24H27ClN4O2	438.9	COC1=C(C=C2C(=C1)C(=NC(=N2)C3CCC3)N4CCN(CC4)C5=CC=CC=C5Cl)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BU0YE2	2-Cyclopropyl-6,7-dimethoxy-4-[4-[(2-methoxyphenyl)methyl]piperazin-1-yl]quinazoline	Investigative	56593288	C25H30N4O3	434.5	COC1=CC=CC=C1CN2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BU27EO	2-(Cyclopropylmethyl)-6,7-dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]quinazoline	Investigative	56593284	C25H30N4O3	434.5	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)CC5CC5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BU58PD	6,7-Dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-methylquinazoline	Investigative	52914826	C22H26N4O3	394.5	CC1=NC2=CC(=C(C=C2C(=N1)N3CCN(CC3)C4=CC=CC=C4OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BV73FR	N-[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-L-leucine	Investigative	44157038	C27H27ClN4O5	523	CC(C)C[C@@H](C(=O)O)NC(=O)C1=NN(C(=C1)C2=C(C=CC=C2OC)OC)C3=C4C=CC(=CC4=NC=C3)Cl	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BWI04R	6-Ethoxy-7-methoxy-2-phenyl-4-(4-phenylpiperazin-1-yl)quinazoline	Investigative	73356948	C27H28N4O2	440.5	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=CC=C5)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BXY9V6	6,7-Dimethoxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylquinazoline	Investigative	4679731	C27H28N4O3	456.5	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5=CC=CC=C5	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BY6EX3	1-{4-[6,7-Dimethoxy-2-(methylethyl)quinazolin-4-yl]piperazinyl}-2-methoxybenzene	Investigative	54758539	C24H30N4O3	422.5	CC(C)C1=NC2=CC(=C(C=C2C(=N1)N3CCN(CC3)C4=CC=CC=C4OC)OC)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BY80TD	6-Ethoxy-4-[4-(2-fluorophenyl)piperazin-1-yl]-7-methoxy-2-phenylquinazoline	Investigative	73346308	C27H27FN4O2	458.5	CCOC1=C(C=C2C(=C1)C(=NC(=N2)C3=CC=CC=C3)N4CCN(CC4)C5=CC=CC=C5F)OC	EC50 ~ 80000 nM	Poor binder
T95605	Neurotensin receptor type 2	BZ4M1Y	1-[4-(2-Cyclopentyl-6,7-dimethoxyquinazolin-4-yl)piperazinyl]-2-methoxybenzene	Investigative	53245571	C26H32N4O3	448.6	COC1=CC=CC=C1N2CCN(CC2)C3=NC(=NC4=CC(=C(C=C43)OC)OC)C5CCCC5	EC50 ~ 80000 nM	Poor binder