TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T95947	Acid-sensing ion channel 3	B17PXI	Tert-butyl 7-[2-[2-(aminomethyl)-3-chloro-1-benzothiophen-6-yl]ethynyl]-3,4-dihydro-1H-isoquinoline-2-carboxylate	Investigative	56659437	C25H25ClN2O2S	453	CC(C)(C)OC(=O)N1CCC2=C(C1)C=C(C=C2)C#CC3=CC4=C(C=C3)C(=C(S4)CN)Cl	IC50 ~ 50000 nM	Poor binder
T95947	Acid-sensing ion channel 3	B39WOT	2-(3-Amino-5-chlorophenyl)-1H-indole-5-carboximidamide	Investigative	25254508	C15H13ClN4	284.74	C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=CC(=CC(=C3)Cl)N	IC50 = 95000 nM	Poor binder
T95947	Acid-sensing ion channel 3	B4DKA7	6-Phenylpyrimidin-4-amine	Investigative	817383	C10H9N3	171.2	C1=CC=C(C=C1)C2=CC(=NC=N2)N	IC50 = 130000 nM	Poor binder
T95947	Acid-sensing ion channel 3	B4NAR8	2-(3-Bromo-5-fluorophenyl)-1H-indole-5-carboximidamide	Investigative	45272658	C15H11BrFN3	332.17	C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=CC(=CC(=C3)Br)F	IC50 = 59000 nM	Poor binder
T95947	Acid-sensing ion channel 3	B7GHB1	2-(3,5-Dibromophenyl)-1H-indole-5-carboximidamide	Investigative	45270105	C15H11Br2N3	393.08	C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=CC(=CC(=C3)Br)Br	IC50 = 59000 nM	Poor binder
T95947	Acid-sensing ion channel 3	B9YM7W	2-(3-Chloro-5-((phenylamino)methyl)phenyl)-1H-indole-5-carboximidamide	Investigative	45270945	C22H19ClN4	374.9	C1=CC=C(C=C1)NCC2=CC(=CC(=C2)Cl)C3=CC4=C(N3)C=CC(=C4)C(=N)N	IC50 = 114000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BA65KF	[3-Chloro-6-[2-[2-(2,2,2-trifluoroethyl)-3,4-dihydro-1H-isoquinolin-7-yl]ethynyl]-1-benzothiophen-2-yl]methanamine	Investigative	56659438	C22H18ClF3N2S	434.9	C1CN(CC2=C1C=CC(=C2)C#CC3=CC4=C(C=C3)C(=C(S4)CN)Cl)CC(F)(F)F	IC50 ~ 50000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BC4VL0	(3-Methoxy-pyridin-2-yl)-(6-methyl-pyridin-2-yl)-amine	Investigative	11413259	C12H13N3O	215.25	CC1=NC(=CC=C1)NC2=C(C=CC=N2)OC	IC50 = 190000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BDWP64	4-(1H-Imidazol-4-YL)-benzylamine	Investigative	29949062	C10H11N3	173.21	C1=CC(=CC=C1CN)C2=CN=CN2	IC50 = 160000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BF4SQ8	2-(2,3,5-Trichlorophenyl)-1H-indole-5-carboximidamide	Investigative	45268405	C15H10Cl3N3	338.6	C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=C(C(=CC(=C3)Cl)Cl)Cl	IC50 = 135000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BFS46X	2-(3-(Benzylamino)-5-chlorophenyl)-1H-indole-5-carboximidamide	Investigative	25254512	C22H19ClN4	374.9	C1=CC=C(C=C1)CNC2=CC(=CC(=C2)C3=CC4=C(N3)C=CC(=C4)C(=N)N)Cl	IC50 = 77000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BGY87Z	2-(3-Chloro-5-methylphenyl)-1H-indole-5-carboximidamide	Investigative	45273577	C16H14ClN3	283.75	CC1=CC(=CC(=C1)Cl)C2=CC3=C(N2)C=CC(=C3)C(=N)N	IC50 = 51000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BMS62X	2-(3,5-Dichlorophenyl)-1H-indole-5-carboximidamide	Investigative	25210286	C15H11Cl2N3	304.2	C1=CC2=C(C=C1C(=N)N)C=C(N2)C3=CC(=CC(=C3)Cl)Cl	IC50 = 133000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BOD54F	2-((5-Methoxy-1H-indol-3-yl)methyl)-6-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydroisoquinoline	Investigative	54581913	C26H23F3N2O	436.5	COC1=CC2=C(C=C1)NC=C2CN3CCC4=C(C3)C=CC(=C4)C5=CC(=CC=C5)C(F)(F)F	IC50 = 103000 nM	Poor binder
T95947	Acid-sensing ion channel 3	BY4F0X	Benzo[b]thiophen-2-ylmethanamine	Investigative	237074	C9H9NS	163.24	C1=CC=C2C(=C1)C=C(S2)CN	IC50 = 97000 nM	Poor binder