TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T98293	PAK-4 protein kinase	B0HX8M	3-Methyl-4-(2-phenoxyacetamido)-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44406048	C15H14N4O3S	330.4	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)COC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	B0N6VA	6-Phenyl-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-4-amine	Investigative	10705154	C13H13N5	239.28	C1CNC2=NC=NC(=C2N=C1C3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	B2VJY5	6-Phenyl-7,8-dihydro-9H-pyrimido[4,5-b][1,4]diazepine-2,4-diamine	Investigative	10538870	C13H14N6	254.29	C1CNC2=NC(=NC(=C2N=C1C3=CC=CC=C3)N)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	B31SIO	6-(3-Methylphenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepin-4-amine	Investigative	44450059	C14H15N5	253.3	CC1=CC(=CC=C1)C2=NC3=C(N=CN=C3NCC2)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BC3K0L	Methyl 3-(piperidin-1-yl)-1H-thieno[2,3-c]pyrazole-5-carboxylate	Investigative	44405987	C13H17N3O2S	279.36	COC(=O)C1=CC2=C(NN=C2S1)CN3CCCCC3	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BEO65U	6-(3-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepin-4-amine	Investigative	44450035	C13H12ClN5	273.72	C1CNC2=NC=NC(=C2N=C1C3=CC(=CC=C3)Cl)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BG63FT	6-(4-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-4-amine	Investigative	10588346	C13H12ClN5	273.72	C1CNC2=NC=NC(=C2N=C1C3=CC=C(C=C3)Cl)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BI3C9W	4-(2-Chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44405999	C14H11ClN4O2S	334.8	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C3=CC=CC=C3Cl	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BN6T4M	5-(1-(2,3-Dichlorobenzyl)-1H-1,2,3-triazol-4-yl)-1H-indazole	Investigative	25166657	C16H11Cl2N5	344.2	C1=CC(=C(C(=C1)Cl)Cl)CN2C=C(N=N2)C3=CC4=C(C=C3)NN=C4	Ki = 67636 nM	Poor binder
T98293	PAK-4 protein kinase	BPMB41	5-(1H-1,2,3-Triazol-4-yl)-1H-indazole	Investigative	25165860	C9H7N5	185.19	C1=CC2=C(C=C1C3=NNN=C3)C=NN2	Ki = 69911 nM	Poor binder
T98293	PAK-4 protein kinase	BPX05I	6-(3-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-2,4-diamine	Investigative	44450033	C13H13ClN6	288.73	C1CNC2=NC(=NC(=C2N=C1C3=CC(=CC=C3)Cl)N)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BQLU06	6-(4-Methylphenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepin-4-amine	Investigative	44450060	C14H15N5	253.3	CC1=CC=C(C=C1)C2=NC3=C(N=CN=C3NCC2)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BRA71K	6-(4-Chlorophenyl)-8,9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine-2,4-diamine	Investigative	10732141	C13H13ClN6	288.73	C1CNC2=NC(=NC(=C2N=C1C3=CC=C(C=C3)Cl)N)N	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BS40OC	3-Methyl-4-(thiophene-2-carboxamido)-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44406055	C12H10N4O2S2	306.4	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BSK3G0	4-(3-Chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44405945	C14H11ClN4O2S	334.8	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BVT45D	Methyl 3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxylate	Investigative	44405982	C8H8N2O2S	196.23	CC1=C2C=C(SC2=NN1)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BWJ84K	4-(4-Chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	Investigative	44405946	C14H11ClN4O2S	334.8	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T98293	PAK-4 protein kinase	BZ1JP2	Methyl 2-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyrazol-4-ylamino)-2-oxoacetate	Investigative	44406047	C10H10N4O4S	282.28	CC1=C2C(=C(SC2=NN1)C(=O)N)NC(=O)C(=O)OC	IC50 ~ 100000 nM	Poor binder