TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T98337	FK506-binding protein 5	D04PGB	Gpi-1046	Terminated	445501	C20H28N2O4	360.4	CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)OCCCC2=CN=CC=C2	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B1CSD8	1-[(2R,13S)-4,6-Dimethoxy-2-methyl-12-oxo-11,17-diazatetracyclo[11.3.1.02,11.03,8]heptadeca-3(8),4,6-trien-17-yl]-2-[(1R,2R)-1,2-dimethylcyclohexyl]ethane-1,2-dione	Investigative	71718375	C28H38N2O5	482.6	C[C@@H]1CCCC[C@@]1(C)C(=O)C(=O)N2[C@H]3CCCC2[C@]4(C5=C(CCN4C3=O)C=C(C=C5OC)OC)C	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B1FOG8	CID 57522349	Investigative	57522349	C31H33F2NO9S	633.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=CC(=C4)F)F)OC	IC50 = 88200 nM	Poor binder
T98337	FK506-binding protein 5	B1YN9J	2-[3-[(1R)-1-[(2S)-1-(1-Benzothiophen-2-ylsulfonyl)piperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522007	C33H35NO9S2	653.8	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=CC=CC=C5S4)OC	IC50 = 67100 nM	Poor binder
T98337	FK506-binding protein 5	B29GBH	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(3,5-dichlorophenyl)sulfonylpiperidine-2-carboxylate	Investigative	57522800	C22H25Cl2NO7S	518.4	COC1=C(C=C(C=C1)OCCOC(=O)[C@@H]2CCCCN2S(=O)(=O)C3=CC(=CC(=C3)Cl)Cl)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B2O6HW	2-[3-[(1R)-1-[(2S)-1-(3,4-Dichlorophenyl)sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522240	C31H33Cl2NO9S	666.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=C(C=C4)Cl)Cl)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B2SEV3	Ethyl 1-[(2-oxo-3H-1,3-benzothiazol-6-yl)sulfonyl]piperidine-2-carboxylate	Investigative	71662582	C15H18N2O5S2	370.4	CCOC(=O)C1CCCCN1S(=O)(=O)C2=CC3=C(C=C2)NC(=O)S3	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B34IZK	2-[3-[3-(3,4-Dimethoxyphenyl)-1-[[(2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carbonyl]amino]propyl]phenoxy]acetic acid	Investigative	70684253	C32H42N2O8	582.7	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)NC(CCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)OCC(=O)O	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B3KMZ1	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(3R)-4-(3,3-dimethyl-2-oxopentanoyl)thiomorpholine-3-carbonyl]oxypropyl]phenoxy]acetic acid	Investigative	57523064	C31H39NO9S	601.7	CCC(C)(C)C(=O)C(=O)N1CCSC[C@H]1C(=O)O[C@H](CCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)OCC(=O)O	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B41QWJ	CID 57522347	Investigative	57522347	C33H39NO11S	657.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=C(C=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B4LOY0	CID 57522570	Investigative	57522570	C33H38N2O10S	654.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C(=C4)N)OCC5)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B5L3ZV	1-[(2R,13S)-4,6-Dimethoxy-2-methyl-12-oxo-11,17-diazatetracyclo[11.3.1.02,11.03,8]heptadeca-3(8),4,6-trien-17-yl]-3,3-dimethylpentane-1,2-dione	Investigative	71720824	C25H34N2O5	442.5	CCC(C)(C)C(=O)C(=O)N1[C@H]2CCCC1[C@]3(C4=C(CCN3C2=O)C=C(C=C4OC)OC)C	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B5XB8K	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-pyrimidin-4-ylsulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid	Investigative	70694726	C29H33N3O9S	599.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=NC=NC=C4)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B6Z0BU	Timcodar	Investigative	9811664	C43H45ClN4O6	749.3	CN([C@@H](CC1=CC=C(C=C1)Cl)C(=O)N(CC2=CC=CC=C2)C(CCC3=CC=NC=C3)CCC4=CC=NC=C4)C(=O)C(=O)C5=CC(=C(C(=C5)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B7NRX8	9-(Benzo[d]thiazol-6-ylsulfonyl)-3-(2-(3,4-dimethoxyphenoxy)-ethyl)-3,9-diazabicyclo[3.3.1]nonan-2-one	Investigative	71716538	C24H27N3O6S2	517.6	COC1=C(C=C(C=C1)OCCN2CC3CCCC(C2=O)N3S(=O)(=O)C4=CC5=C(C=C4)N=CS5)OC	Ki = 64800 nM	Poor binder
T98337	FK506-binding protein 5	B7QX2W	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(1,3-benzothiazol-6-ylsulfonyl)piperidine-2-carboxylate	Investigative	57522801	C23H26N2O7S2	506.6	COC1=C(C=C(C=C1)OCCOC(=O)[C@@H]2CCCCN2S(=O)(=O)C3=CC4=C(C=C3)N=CS4)OC	IC50 = 66270 nM	Poor binder
T98337	FK506-binding protein 5	B91KPY	[(1R)-3-(3,4-Dimethoxyphenyl)-1-[3-(2-morpholin-4-ylethoxy)phenyl]propyl] (2S)-1-[(2R,3S)-2-cyclohexyl-3-hydroxy-3-phenylpropanoyl]piperidine-2-carboxylate	Investigative	122192639	C44H58N2O8	742.9	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4C(=O)[C@H](C5CCCCC5)[C@@H](C6=CC=CC=C6)O)OC	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B9S4OK	CID 57522685	Investigative	57522685	C32H34N2O11S	654.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C=C4)NC(=O)O5)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	B9T7AE	(2S)-N-[(2S)-1-Amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxamide	Investigative	117967826	C26H39N3O7	505.6	COC1=CC(=CC(=C1OC)OC)[C@H](C2CCCCC2)C(=O)N3CCCC[C@H]3C(=O)N[C@@H](CO)C(=O)N	Ki = 62900 nM	Poor binder
T98337	FK506-binding protein 5	B9ZD3R	(2R,13S)-17-(3,5-Dichloro-4-hydroxyphenyl)sulfonyl-4,6-dimethoxy-2-methyl-11,17-diazatetracyclo[11.3.1.02,11.03,8]heptadeca-3(8),4,6-trien-12-one	Investigative	71720180	C24H26Cl2N2O6S	541.4	C[C@@]12C3CCC[C@H](N3S(=O)(=O)C4=CC(=C(C(=C4)Cl)O)Cl)C(=O)N1CCC5=C2C(=CC(=C5)OC)OC	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BA1IR3	(S)-1-(3,3-Dimethyl-2-oxo-pentanoyl)-piperidine-2-carboxylic acid 3-pyridin-3-yl-propyl ester	Investigative	9820942	C21H30N2O4	374.5	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)OCCCC2=CN=CC=C2	IC50 ~ 150000 nM	Poor binder
T98337	FK506-binding protein 5	BA2M3B	CID 57521881	Investigative	57521881	C35H37N3O9S	675.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC=C(C=C4)C5=NC=CC=N5)OC	IC50 = 62800 nM	Poor binder
T98337	FK506-binding protein 5	BAU81E	CID 57522684	Investigative	57522684	C33H36N2O10S	652.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C=C4)NC(=O)C5)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BB34GP	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate	Investigative	57521460	C23H33NO7	435.5	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)OCCOC2=CC(=C(C=C2)OC)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BC5D3V	CID 57522927	Investigative	57522927	C31H39NO9	569.6	CCC(C)(C)C(=O)C(=O)N1CCC[C@H]1C(=O)O[C@H](CCC2=CC(=C(C=C2)OC)OC)C3=CC(=CC=C3)OCC(=O)O	IC50 = 51500 nM	Poor binder
T98337	FK506-binding protein 5	BCB94E	2-(3,4-Dimethoxyphenoxy)ethyl (2S)-1-[2-[(1S,2R)-2-ethyl-1-hydroxycyclohexyl]-2-oxoacetyl]piperidine-2-carboxylate	Investigative	70694756	C26H37NO8	491.6	CC[C@@H]1CCCC[C@]1(C(=O)C(=O)N2CCCC[C@H]2C(=O)OCCOC3=CC(=C(C=C3)OC)OC)O	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BCJ03A	2-[3-[(1R)-1-[(2S)-1-[3,5-Bis(methoxycarbonyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522456	C35H39NO13S	713.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=CC(=C4)C(=O)OC)C(=O)OC)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BD0ON4	1-[3-[2-(3,4-Dimethoxyphenoxy)ethyl]-2-oxo-3,9-diazabicyclo[3.3.1]nonan-9-yl]-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione	Investigative	71717767	C28H34N2O9	542.6	COC1=C(C=C(C=C1)OCCN2CC3CCCC(C2=O)N3C(=O)C(=O)C4=CC(=C(C(=C4)OC)OC)OC)OC	Ki = 51100 nM	Poor binder
T98337	FK506-binding protein 5	BE1I0W	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[(2S)-1-(2-methylpyrimidin-4-yl)sulfonylpiperidine-2-carbonyl]oxypropyl]phenoxy]acetic acid	Investigative	70694725	C30H35N3O9S	613.7	CC1=NC=CC(=N1)S(=O)(=O)N2CCCC[C@H]2C(=O)O[C@H](CCC3=CC(=C(C=C3)OC)OC)C4=CC(=CC=C4)OCC(=O)O	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BEAB57	(2R,13S)-17-(3,5-Dichlorophenyl)sulfonyl-4,6-dimethoxy-2-methyl-11,17-diazatetracyclo[11.3.1.02,11.03,8]heptadeca-3(8),4,6-trien-12-one	Investigative	71718376	C24H26Cl2N2O5S	525.4	C[C@@]12C3CCC[C@H](N3S(=O)(=O)C4=CC(=CC(=C4)Cl)Cl)C(=O)N1CCC5=C2C(=CC(=C5)OC)OC	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BHO45G	(2S)-1-[(2S)-2-Cyclohexyl-2-(3,4,5-trimethoxyphenyl)acetyl]-N-ethylpiperidine-2-carboxamide	Investigative	117968011	C25H38N2O5	446.6	CCNC(=O)[C@@H]1CCCCN1C(=O)[C@@H](C2CCCCC2)C3=CC(=C(C(=C3)OC)OC)OC	Ki = 55000 nM	Poor binder
T98337	FK506-binding protein 5	BJ04FY	CID 57522237	Investigative	57522237	C31H34FNO9S	615.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC=CC(=C4)F)OC	IC50 = 54050 nM	Poor binder
T98337	FK506-binding protein 5	BK0E3Y	2-[3-[(1R)-1-[(2S)-1-[3,5-Bis(trifluoromethyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522350	C33H33F6NO9S	733.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BKO21J	2-[3-[(1R)-1-[(2S)-1-[3-Bromo-5-(trifluoromethyl)phenyl]sulfonylpiperidine-2-carbonyl]oxy-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57522455	C32H33BrF3NO9S	744.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=CC(=C4)C(F)(F)F)Br)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BL19CE	2-[3-[(1R)-1-[[(2S)-1-(3,5-Dichloro-4-hydroxyphenyl)sulfonylpiperidine-2-carbonyl]amino]-3-(3,4-dimethoxyphenyl)propyl]phenoxy]acetic acid	Investigative	57523068	C31H34Cl2N2O9S	681.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)NC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC(=C(C(=C4)Cl)O)Cl)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BLP6S7	2-[3-[(1R)-3-(3,4-Dimethoxyphenyl)-1-[[(2S)-1-[(2-oxo-3H-1,3-benzothiazol-6-yl)sulfonyl]piperidine-2-carbonyl]amino]propyl]phenoxy]acetic acid	Investigative	57523069	C32H35N3O9S2	669.8	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)NC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=CC5=C(C=C4)NC(=O)S5)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BMO97R	2-(3,4-Dimethoxyphenoxy)ethyl 1-(3,5-dichlorophenyl)sulfonylpiperidine-2-carboxylate	Investigative	71662579	C22H25Cl2NO7S	518.4	COC1=C(C=C(C=C1)OCCOC(=O)C2CCCCN2S(=O)(=O)C3=CC(=CC(=C3)Cl)Cl)OC	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BN3B1Q	2-(3,4-Dimethoxyphenoxy)ethyl 1-(1,3-benzothiazol-6-ylsulfonyl)piperidine-2-carboxylate	Investigative	71662580	C23H26N2O7S2	506.6	COC1=C(C=C(C=C1)OCCOC(=O)C2CCCCN2S(=O)(=O)C3=CC4=C(C=C3)N=CS4)OC	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BO8R1Z	CID 57522929	Investigative	57522929	C36H44Cl2N2O9S	751.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC(=C(C(=C5)Cl)OC)Cl)OC	IC50 ~ 50000 nM	Poor binder
T98337	FK506-binding protein 5	BSQ36K	2-(3,4-Dimethoxyphenoxy)ethyl 1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate	Investigative	71662419	C27H33NO10	531.6	COC1=C(C=C(C=C1)OCCOC(=O)C2CCCCN2C(=O)C(=O)C3=CC(=C(C(=C3)OC)OC)OC)OC	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BTKO61	CID 57522803	Investigative	57522803	C36H43N3O8S2	709.9	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC6=C(C=C5)N=CS6)OC	IC50 ~ 50000 nM	Poor binder
T98337	FK506-binding protein 5	BU1CW6	CID 57522006	Investigative	57522006	C29H33NO10S	587.6	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCC(=O)O)OC(=O)[C@@H]3CCCCN3S(=O)(=O)C4=COC=C4)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BW5V7F	1-(3-Ethyl-2-oxo-3,9-diazabicyclo[3.3.1]nonan-9-yl)-2-(3,4,5-trimethoxyphenyl)ethane-1,2-dione	Investigative	71717142	C20H26N2O6	390.4	CCN1CC2CCCC(C1=O)N2C(=O)C(=O)C3=CC(=C(C(=C3)OC)OC)OC	Ki ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BX8Z3L	Methyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate	Investigative	11129344	C14H23NO4	269.34	CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)OC	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BXYE40	2-(3,4-Dimethoxyphenyl)ethyl (2S)-1-[2-[(1S,2R)-1-hydroxy-2-methylcyclohexyl]-2-oxoacetyl]piperidine-2-carboxylate	Investigative	70688508	C25H35NO7	461.5	C[C@@H]1CCCC[C@]1(C(=O)C(=O)N2CCCC[C@H]2C(=O)OCCC3=CC(=C(C=C3)OC)OC)O	IC50 ~ 100000 nM	Poor binder
T98337	FK506-binding protein 5	BZTN10	CID 57522802	Investigative	57522802	C35H42Cl2N2O8S	721.7	COC1=C(C=C(C=C1)CC[C@H](C2=CC(=CC=C2)OCCN3CCOCC3)OC(=O)[C@@H]4CCCCN4S(=O)(=O)C5=CC(=CC(=C5)Cl)Cl)OC	IC50 ~ 50000 nM	Poor binder