Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T48703 | Target Info | |||
| Target Name | Toll-like receptor 8 (TLR8) | ||||
| Synonyms |
UNQ249/PRO286; CD288 antigen; CD288
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| Target Type | Clinical trial Target | ||||
| Gene Name | TLR8 | ||||
| Biochemical Class | Toll-like receptor | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Toll-like receptor 7 (TLR7) | Successful Target | ||||
| UniProt ID | TLR7_HUMAN | |||||
| Gene Name | TLR7 | |||||
| Synonyms |
Toll-like receptor 7
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| Representative Drug(s) | Resiquimod | Drug Info | EC50 = 260.1 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept. J Med Chem. 2010 Apr 8;53(7):2964-72. | ||||
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