Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06QDR
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| Former ID |
DNAP001495
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| Drug Name |
Choline alfoscerate
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| Synonyms |
Delecit (TN)
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| Drug Type |
Small molecular drug
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| Indication | Amnesia [ICD-11: MB21.1; ICD-10: R41, R41.3] | Approved | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H20NO6P
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| Canonical SMILES |
C[N+](C)(C)CCOP(=O)([O-])OCC(CO)O
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| InChI |
1S/C8H20NO6P/c1-9(2,3)4-5-14-16(12,13)15-7-8(11)6-10/h8,10-11H,4-7H2,1-3H3/t8-/m1/s1
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| InChIKey |
SUHOQUVVVLNYQR-MRVPVSSYSA-N
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| CAS Number |
CAS 28319-77-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:16870
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| SuperDrug ATC ID |
N07AX02
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Muscarinic acetylcholine receptor M5 (CHRM5) | Target Info | Modulator | [2] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Cholinergic synapse | ||||
| Regulation of actin cytoskeleton | ||||
| Panther Pathway | Alzheimer disease-amyloid secretase pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Reactome | Muscarinic acetylcholine receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Monoamine GPCRs | |||
| Calcium Regulation in the Cardiac Cell | ||||
| Regulation of Actin Cytoskeleton | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 467). | |||
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