Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08OUU
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| Former ID |
DIB013260
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| Drug Name |
Genevx
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| Synonyms |
Ad5-VEGF145; Restenosis therapy, Collateral; VEGF gene therapy, Collateral
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Terminated | [1] | |
| Company |
Collateral Therapeutics Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vascular endothelial growth factor receptor (VEGFR) | Target Info | Modulator | [2] |
| KEGG Pathway | Ras signaling pathway | |||
| Rap1 signaling pathway | ||||
| Cytokine-cytokine receptor interaction | ||||
| HIF-1 signaling pathway | ||||
| Endocytosis | ||||
| PI3K-Akt signaling pathway | ||||
| Focal adhesion | ||||
| Transcriptional misregulation in cancer | ||||
| Rheumatoid arthritis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013170) | |||
| REF 2 | Vascular Endothelial Growth Factor Gene Therapy Increases Survival, Promotes Lung Angiogenesis, and Prevents Alveolar Damage in Hyperoxia-Induced Lung Injury. Circulation. 2005; 112: 2477-2486. | |||
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