Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V6IE
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| Former ID |
DIB020670
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| Drug Name |
pentanoic acid
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| Synonyms |
n-pentanoic acid; N-valeric acid; valeric acid; pentanoate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C5H10O2
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| Canonical SMILES |
CCCCC(=O)O
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| InChI |
1S/C5H10O2/c1-2-3-4-5(6)7/h2-4H2,1H3,(H,6,7)
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| InChIKey |
NQPDZGIKBAWPEJ-UHFFFAOYSA-N
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| CAS Number |
CAS 109-52-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4061, 476725, 584342, 587066, 607040, 3135187, 5573677, 7849659, 7888625, 7889790, 7890462, 8144608, 8155532, 10503738, 11528583, 14818108, 24846964, 24886773, 24901465, 29204661, 29226745, 30862566, 31067212, 31571900, 32626207, 38279762, 38395473, 46393660, 46505166, 46506373, 47193677, 48414847, 48417212, 57324659, 80633880, 81060692, 85165144, 85177176, 87577803, 88823097, 92251276, 103176196, 104316578, 104667383, 118303833, 124811698, 124894346, 124894347, 125337643, 126523654
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| ChEBI ID |
CHEBI:17418
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Free fatty acid receptor 2 (FFAR2) | Target Info | Agonist | [2] |
| Free fatty acid receptor 3 (FFAR3) | Target Info | Agonist | [3] | |
| KEGG Pathway | cAMP signaling pathway | |||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1061). | |||
| REF 2 | The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids. J Biol Chem. 2003 Mar 28;278(13):11312-9. | |||
| REF 3 | Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci U S A. 2004 Jan 27;101(4):1045-50. | |||
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