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| Target and Pathway |
Top |
| Target(s) |
Prostaglandin E2 receptor EP1 (PTGER1) |
Target Info
|
Antagonist |
[2] |
| Prostaglandin E2 receptor EP2 (PTGER2) |
Target Info
|
Antagonist |
[2], [3] |
| Prostaglandin E2 receptor EP3 (PTGER3) |
Target Info
|
Antagonist |
[2] |
| Prostaglandin E2 receptor EP4 (PTGER4) |
Target Info
|
Antagonist |
[2] |
| Prostaglandin F2-alpha receptor (PTGFR) |
Target Info
|
Antagonist |
[2] |
| References |
Top |
| REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3379).
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| REF 2 |
Evaluation of WO 2012/177618 A1 and US-2014/0179750 A1: novel small molecule antagonists of prostaglandin-E2 receptor EP2.Expert Opin Ther Pat. 2015 Jul;25(7):837-44.
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| REF 3 |
Synthesis and evaluation of a gamma-lactam as a highly selective EP2 and EP4 receptor agonist. Bioorg Med Chem Lett. 2008 Jan 15;18(2):821-4.
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