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| Target and Pathway |
Top |
| Target(s) |
Cyclin-dependent kinase 1 (CDK1) |
Target Info
|
Inhibitor |
[2] |
| Cyclin-dependent kinase 4 (CDK4) |
Target Info
|
Inhibitor |
[3] |
| References |
Top |
| REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7934).
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| REF 2 |
P276-00, a novel cyclin-dependent inhibitor induces G1-G2 arrest, shows antitumor activity on cisplatin-resistant cells and significant in vivo efficacy in tumor models. Mol Cancer Ther. 2007 Mar;6(3):926-34.
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| REF 3 |
Liposarcoma: molecular genetics and therapeutics. Sarcoma. 2011;2011:483154.
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