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Target and Pathway |
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Target(s) |
Glucocorticoid receptor messenger RNA (GCR mRNA) |
Target Info
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Inhibitor |
[2] |
References |
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REF 1 |
Liver-selective glucocorticoid receptor antagonism decreases glucose production and increases glucose disposal, ameliorating insulin resistance. Metabolism. 2007 Mar;56(3):380-7.
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REF 2 |
Synthesis and activity of novel bile-acid conjugated glucocorticoid receptor antagonists. Bioorg Med Chem Lett. 2006 Dec 1;16(23):6086-90.
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