Drug Information
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | 5-HT 1A receptor (HTR1A) | Target Info | Agonist | [1], [2] |
5-HT 2A receptor (HTR2A) | Target Info | Antagonist | [1], [2] |
References | Top | |||
---|---|---|---|---|
REF 1 | Novel drugs and therapeutic targets for severe mood disorders. Neuropsychopharmacology. 2008 Aug;33(9):2080-92. | |||
REF 2 | Synthesis and SAR of adatanserin: novel adamantyl aryl- and heteroarylpiperazines with dual serotonin 5-HT(1A) and 5-HT(2) activity as potential anxiolytic and antidepressant agents. J Med Chem. 1999Dec 16;42(25):5077-94. |
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