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Target and Pathway |
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Target(s) |
Transient receptor potential cation channel V1 (TRPV1) |
Target Info
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Inhibitor |
[2] |
Transient receptor potential cation channel V4 (TRPV4) |
Target Info
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Inhibitor |
[3] |
References |
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REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4230).
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REF 2 |
Silicon switch approach in TRPV1 antagonist MK-056 and its analogues. Bioorg Med Chem. 2010 Jan 1;18(1):111-6.
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REF 3 |
Novel non-vanilloid VR1 antagonist of high analgesic effects and its structural requirement for VR1 antagonistic effects. Bioorg Med Chem Lett. 2003 Dec 15;13(24):4389-93.
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