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Target and Pathway |
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Target(s) |
DNA topoisomerase I (TOP1) |
Target Info
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Inhibitor |
[2], [3] |
References |
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REF 1 |
ClinicalTrials.gov (NCT00005869) Nitrocamptothecin Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced or Metastatic Pancreatic Cancer. U.S. National Institutes of Health.
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REF 2 |
Rubitecan. Expert Opin Investig Drugs. 2006 Jan;15(1):71-9.
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REF 3 |
A Phase I study of 9-nitrocamptothecin given concurrently with capecitabine in patients with refractory, metastatic solid tumors. Cancer. 2003 Jan 1;97(1):148-54.
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