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| Target and Pathway |
Top |
| Target(s) |
Vascular endothelial growth factor receptor 2 (KDR) |
Target Info
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Inhibitor |
[1] |
| Vascular endothelial growth factor receptor 3 (FLT-4) |
Target Info
|
Inhibitor |
[2] |
| VEGFR1 messenger RNA (VEGFR1 mRNA) |
Target Info
|
Inhibitor |
[2] |
| References |
Top |
| REF 1 |
Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharm... Bioorg Med Chem Lett. 2002 Dec 16;12(24):3537-41.
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| REF 2 |
Synthesis and initial SAR studies of 3,6-disubstituted pyrazolo[1,5-a]pyrimidines: a new class of KDR kinase inhibitors. Bioorg Med Chem Lett. 2002 Oct 7;12(19):2767-70.
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