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Target and Pathway |
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Target(s) |
GABA(A) receptor alpha-1 (GABRA1) |
Target Info
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Inhibitor |
[1] |
GABA(A) receptor beta-2 (GABRB2) |
Target Info
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Inhibitor |
[1] |
GABA(A) receptor gamma-2 (GABRG2) |
Target Info
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Inhibitor |
[1] |
Gamma-aminobutyric acid receptor (GAR) |
Target Info
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Inhibitor |
[2] |
References |
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REF 1 |
Potent 4-aryl- or 4-arylalkyl-substituted 3-isoxazolol GABA(A) antagonists: synthesis, pharmacology, and molecular modeling. J Med Chem. 2005 Jan 27;48(2):427-39.
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REF 2 |
4-aryl-5-(4-piperidyl)-3-isoxazolol GABAA antagonists: synthesis, pharmacology, and structure-activity relationships. J Med Chem. 2007 Apr 19;50(8):1988-92.
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