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| Target and Pathway |
Top |
| Target(s) |
Farnesyl protein transferase (Ftase) |
Target Info
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Modulator |
[4] |
| References |
Top |
| REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8026).
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| REF 2 |
ClinicalTrials.gov (NCT00006242) BMS-214662 in Treating Patients With Advanced Solid Tumors. U.S. National Institutes of Health.
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| REF 3 |
ClinicalTrials.gov (NCT00022529) BMS-214662 Plus Trastuzumab in Treating Patients With Advanced Solid Tumors. U.S. National Institutes of Health.
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| REF 4 |
Farnesyltransferase inhibitor BMS-214662 induces apoptosis in B-cell chronic lymphocytic leukemia cells. Leukemia. 2004 Oct;18(10):1599-604.
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