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| Target and Pathway |
Top |
| Target(s) |
Neuronal acetylcholine receptor alpha-7 (CHRNA7) |
Target Info
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Agonist |
[2], [3] |
| References |
Top |
| REF 1 |
ClinicalTrials.gov (NCT02432066) Effects of GTS-21 on Smoking Behavior and Neurocognitive Functions. U.S. National Institutes of Health.
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| REF 2 |
The brain alpha7 nicotinic receptor may be an important therapeutic target for the treatment of Alzheimer's disease: studies with DMXBA (GTS-21). Behav Brain Res. 2000 Aug;113(1-2):169-81.
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| REF 3 |
Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology (Berl). 1998 Apr;136(4):320-7.
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