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Target and Pathway |
Top |
Target(s) |
C-X-C chemokine receptor type 1 (CXCR1) |
Target Info
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Inhibitor |
[1] |
C-X-C chemokine receptor type 2 (CXCR2) |
Target Info
|
Inhibitor |
[1] |
Interleukin-8 (IL8) |
Target Info
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Inhibitor |
[2] |
Prostaglandin G/H synthase 1 (COX-1) |
Target Info
|
Inhibitor |
[1] |
Prostaglandin G/H synthase 2 (COX-2) |
Target Info
|
Inhibitor |
[1] |
References |
Top |
REF 1 |
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors. J Med Chem. 2005 Jun 30;48(13):4312-31.
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REF 2 |
Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4026-30.
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