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REF 1 |
Signal-transducing adaptor protein-2 regulates integrin-mediated T cell adhesion through protein degradation of focal adhesion kinase. J Immunol. 2007 Aug 15;179(4):2397-407.
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REF 2 |
c-Cbl ubiquitin ligase regulates focal adhesion protein turnover and myofibril degeneration induced by neutrophil protease cathepsin G. J Biol Chem. 2012 Feb 17;287(8):5327-39.
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REF 3 |
FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol. 2000 May;2(5):249-56.
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REF 4 |
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts. J Cell Biol. 1999 Mar 8;144(5):1019-31.
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A directed protein interaction network for investigating intracellular signal transduction. Sci Signal. 2011 Sep 6;4(189):rs8.
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Nck-2 interacts with focal adhesion kinase and modulates cell motility. Int J Biochem Cell Biol. 2002 Jul;34(7):791-805.
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Structure and function of Cas-L, a 105-kD Crk-associated substrate-related protein that is involved in beta 1 integrin-mediated signaling in lymphocytes. J Exp Med. 1996 Oct 1;184(4):1365-75.
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REF 8 |
Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions. J Biol Chem. 1998 Jan 9;273(2):1003-14.
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REF 9 |
PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway. J Biol Chem. 1999 Jul 16;274(29):20693-703.
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Tumor suppressor PTEN inhibition of cell invasion, migration, and growth: differential involvement of focal adhesion kinase and p130Cas. Cancer Res. 1999 Jan 15;59(2):442-9.
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Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling. J Cell Biol. 2002 Apr 1;157(1):149-60.
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REF 12 |
Thrombspondin acts via integrin-associated protein to activate the platelet integrin alphaIIbbeta3. J Biol Chem. 1997 Jun 6;272(23):14740-6.
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Differential regulation of cell motility and invasion by FAK. J Cell Biol. 2003 Mar 3;160(5):753-67.
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Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin. J Neurochem. 2003 Jan;84(2):253-65.
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Site-specific phosphorylation of platelet focal adhesion kinase by low-density lipoprotein. Biochem J. 2003 Jan 15;369(Pt 2):407-16.
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MMP-9 silencing regulates hTERT expression via 1 integrin-mediated FAK signaling and induces senescence in glioma xenograft cells. Cell Signal. 2011 Dec;23(12):2065-75.
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REF 17 |
Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network. J Proteome Res. 2014 Dec 5;13(12):5339-46.
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REF 18 |
Insulin receptor substrate-1 as a signaling molecule for focal adhesion kinase pp125(FAK) and pp60(src). J Biol Chem. 1998 Nov 27;273(48):32244-53.
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REF 19 |
Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase. J Cell Biol. 1995 May;129(3):831-42.
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REF 20 |
Phosphatidylinositol 3-kinase activation and interaction with focal adhesion kinase in Escherichia coli K1 invasion of human brain microvascular endothelial cells. J Biol Chem. 2000 Nov 24;275(47):36769-74.
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REF 21 |
The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92.
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REF 22 |
In silico prediction of physical protein interactions and characterization of interactome orphans. Nat Methods. 2015 Jan;12(1):79-84.
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REF 23 |
Neuregulin-1 enhances motility and migration of human astrocytic glioma cells. J Biol Chem. 2003 Jun 6;278(23):20971-8.
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REF 24 |
The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases. J Biol Chem. 2001 May 18;276(20):17199-205.
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A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
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Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation. Mol Cell. 2008 Jan 18;29(1):9-22.
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REF 27 |
Focal adhesion kinase activates Stat1 in integrin-mediated cell migration and adhesion. J Biol Chem. 2001 Jun 1;276(22):19512-23.
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REF 28 |
Regulation of neutrophil adhesion by pituitary growth hormone accompanies tyrosine phosphorylation of Jak2, p125FAK, and paxillin. J Immunol. 2000 Aug 15;165(4):2116-23.
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REF 29 |
A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration. J Biol Chem. 2002 Jun 7;277(23):20887-94.
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REF 30 |
Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C. Blood. 2000 Apr 15;95(8):2505-13.
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REF 31 |
Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion. J Biol Chem. 1998 Jan 23;273(4):2384-9.
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REF 32 |
Pyk2 and FAK regulate neurite outgrowth induced by growth factors and integrins. Nat Cell Biol. 2000 Sep;2(9):574-81.
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REF 33 |
SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis. Immunity. 2007 Nov;27(5):811-23.
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REF 34 |
Negative regulation of FAK signaling by SOCS proteins. EMBO J. 2003 Oct 1;22(19):5036-46.
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REF 35 |
Methylation silencing of SOCS-3 promotes cell growth and migration by enhancing JAK/STAT and FAK signalings in human hepatocellular carcinoma. Oncogene. 2005 Sep 22;24(42):6406-17.
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REF 36 |
Phospho-tyrosine dependent protein-protein interaction network. Mol Syst Biol. 2015 Mar 26;11(3):794.
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