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| Target General Information |
Top |
| Target ID |
T58307 |
Target Info
|
| Target Name |
Protein phosphatase methylesterase 1 (PME-1) |
| Synonyms |
PRO0750; PP2593; PME1 |
| Target Type |
Patented-recorded Target |
| Gene Name |
PPME1 |
| Biochemical Class |
Carboxylic ester hydrolase |
| UniProt ID |
|
| Target Interacting Proteins |
Top |
| Ester hydrolases |
[+] 3 Ester hydrolases |
+ |
| Interacting Target Name |
Serine/threonine PP2A-alpha (PPP2CA) |
Clinical trial Target |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; RP-C; Replication protein C; PP2A-alpha |
| Evidence Score (E-score) |
4 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-MS |
[2] |
| 3 |
Affinity Capture-MS |
[3] |
| 4 |
Affinity Capture-Western |
[4] |
| Interacting Protein Name |
PP2A subunit A isoform PR65-alpha (PPP2R1A) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
PP2A.Aalpha; PP2AAALPHA; PR65A |
| Evidence Score (E-score) |
3 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-MS |
[4] |
| 3 |
Affinity Capture-Western |
[4] |
| Interacting Protein Name |
Protein phosphatase 2 catalytic subunit beta (PPP2CB) |
Interacting Protein |
Interacting Protein Info
|
| UniProt ID |
|
| Synonyms |
PP2Abeta; PP2CB |
| Evidence Score (E-score) |
2 Experimental Evidences |
+ |
| 1 |
Affinity Capture-MS |
[1] |
| 2 |
Affinity Capture-MS |
[4] |
| References |
Top |
| REF 1 |
An integrated workflow for charting the human interaction proteome: insights into the PP2A system. Mol Syst Biol. 2009;5:237.
|
| REF 2 |
Architecture of the human interactome defines protein communities and disease networks. Nature. 2017 May 25;545(7655):505-509.
|
| REF 3 |
The BioPlex Network: A Systematic Exploration of the Human Interactome. Cell. 2015 Jul 16;162(2):425-440.
|
| REF 4 |
Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data. Mol Cell Proteomics. 2015 Dec;14(12):3274-83.
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