| References |
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| REF 1 |
The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127.
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| REF 2 |
BMI1 confers radioresistance to normal and cancerous neural stem cells through recruitment of the DNA damage response machinery. J Neurosci. 2010 Jul 28;30(30):10096-111.
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| REF 3 |
Several distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locus. PLoS One. 2009 Jul 28;4(7):e6380.
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| REF 4 |
PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes. Mol Cell. 2012 Feb 10;45(3):344-56.
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| REF 5 |
A High-Density Map for Navigating the Human Polycomb Complexome. Cell Rep. 2016 Oct 4;17(2):583-595.
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| REF 6 |
BMI1-UBR5 axis regulates transcriptional repression at damaged chromatin. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11243-11248.
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| REF 7 |
The polycomb protein Ring1B generates self atypical mixed ubiquitin chains required for its in vitro histone H2A ligase activity. Mol Cell. 2006 Dec 8;24(5):701-711.
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| REF 8 |
The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells. J Biol Chem. 2016 Jan 1;291(1):182-97.
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| REF 9 |
Monoubiquitination of H2AX protein regulates DNA damage response signaling. J Biol Chem. 2011 Aug 12;286(32):28599-607.
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| REF 10 |
Role of Bmi1 in H2A ubiquitylation and Hox gene silencing. J Biol Chem. 2006 Aug 11;281(32):22537-44.
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| REF 11 |
The Bmi-1 helix-turn and ring finger domains are required for Bmi-1 antagonism of (-) epigallocatechin-3-gallate suppression of skin cancer cell survival. Cell Signal. 2015 Jul;27(7):1336-44.
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| REF 12 |
Structure of a Bmi-1-Ring1B polycomb group ubiquitin ligase complex. J Biol Chem. 2006 Jul 21;281(29):20643-9.
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| REF 13 |
Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing. Mol Cell. 2005 Dec 22;20(6):845-54.
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| REF 14 |
BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase. Nat Commun. 2015 Jul 7;6:7621.
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| REF 15 |
RING1 is associated with the polycomb group protein complex and acts as a transcriptional repressor. Mol Cell Biol. 1997 Jul;17(7):4105-13.
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| REF 16 |
ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression. Cancer Cell. 2012 Aug 14;22(2):180-93.
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| REF 17 |
The PRC1 Polycomb group complex interacts with PLZF/RARA to mediate leukemic transformation. Genes Dev. 2009 May 15;23(10):1195-206.
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| REF 18 |
A proteome-scale map of the human interactome network. Cell. 2014 Nov 20;159(5):1212-1226.
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| REF 19 |
Polycomb group protein-associated chromatin is reproduced in post-mitotic G1 phase and is required for S phase progression. J Biol Chem. 2008 Jul 4;283(27):18905-15.
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| REF 20 |
MDR1 mediated chemoresistance: BMI1 and TIP60 in action. Biochim Biophys Acta. 2016 Aug;1859(8):983-93.
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| REF 21 |
A human protein-protein interaction network: a resource for annotating the proteome. Cell. 2005 Sep 23;122(6):957-68.
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| REF 22 |
Radiosensitization of esophageal carcinoma cells by the silencing of BMI-1. Oncol Rep. 2016 Jun;35(6):3669-78.
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| REF 23 |
BMI1 is recruited to DNA breaks and contributes to DNA damage-induced H2A ubiquitination and repair. Mol Cell Biol. 2011 May;31(10):1972-82.
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| REF 24 |
Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex. EMBO J. 2011 Jul 19;30(16):3285-97.
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| REF 25 |
In Vitro Assay to Study Histone Ubiquitination During Transcriptional Regulation. Methods Mol Biol. 2017;1507:235-244.
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| REF 26 |
Ubiquitin-specific proteases 7 and 11 modulate Polycomb regulation of the INK4a tumour suppressor. EMBO J. 2010 Aug 4;29(15):2553-65.
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| REF 27 |
Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling. Dev Cell. 2002 Oct;3(4):499-510.
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| REF 28 |
Identification and characterization of interactions between the vertebrate polycomb-group protein BMI1 and human homologs of polyhomeotic. Mol Cell Biol. 1997 Apr;17(4):2326-35.
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| REF 29 |
BMI1 regulates PRC1 architecture and activity through homo- and hetero-oligomerization. Nat Commun. 2016 Nov 9;7:13343.
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| REF 30 |
Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 2015 Apr 23;161(3):647-660.
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| REF 31 |
Structure of the polycomb group protein PCGF1 in complex with BCOR reveals basis for binding selectivity of PCGF homologs. Structure. 2013 Apr 2;21(4):665-71.
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| REF 32 |
Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells. Mol Cell Proteomics. 2011 Apr;10(4):M110.002642.
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