| Drug General Information |
| Drug ID |
D01UJL
|
| Former ID |
DNC002646
|
| Drug Name |
N-Trimethyllysine
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C9H21N2O2+
|
| Canonical SMILES |
C[N+](C)(C)CCCCC(C(=O)O)N
|
| InChI |
1S/C9H20N2O2/c1-11(2,3)7-5-4-6-8(10)9(12)13/h8H,4-7,10H2,1-3H3/p+1/t8-/m0/s1
|
| InChIKey |
MXNRLFUSFKVQSK-QMMMGPOBSA-O
|
| PubChem Compound ID |
|
| PubChem Substance ID |
8145614, 10298540, 11534265, 34882549, 36884232, 50002539, 57403298, 78432042, 104250328, 104622279, 127761927, 135073467, 136062410, 144235463, 152198898, 198975193, 226541855
|
| Target and Pathway |
| Target(s) |
Calmodulin |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Ras signaling pathway
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Rap1 signaling pathway
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Calcium signaling pathway
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cGMP-PKG signaling pathway
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cAMP signaling pathway
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Phosphatidylinositol signaling system
|
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Oocyte meiosis
|
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Adrenergic signaling in cardiomyocytes
|
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Vascular smooth muscle contraction
|
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Circadian entrainment
|
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Long-term potentiation
|
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Neurotrophin signaling pathway
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Dopaminergic synapse
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Olfactory transduction
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Phototransduction
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Inflammatory mediator regulation of TRP channels
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Insulin signaling pathway
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GnRH signaling pathway
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Estrogen signaling pathway
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Melanogenesis
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Oxytocin signaling pathway
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Glucagon signaling pathway
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Salivary secretion
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Gastric acid secretion
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Alzheimer's disease
|
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Amphetamine addiction
|
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Alcoholism
|
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Pertussis
|
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Tuberculosis
|
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Glioma
|
|
NetPath Pathway
|
RANKL Signaling Pathway
|
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TSH Signaling Pathway
|
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PANTHER Pathway
|
CCKR signaling map ST
|
|
Pathway Interaction Database
|
BCR signaling pathway
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p38 MAPK signaling pathway
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Calcineurin-regulated NFAT-dependent transcription in lymphocytes
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Role of Calcineurin-dependent NFAT signaling in lymphocytes
|
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IL2 signaling events mediated by PI3K
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IFN-gamma pathway
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Lissencephaly gene (LIS1) in neuronal migration and development
|
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ErbB1 downstream signaling
|
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VEGFR1 specific signals
|
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Regulation of cytoplasmic and nuclear SMAD2/3 signaling
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Calcium signaling in the CD4+ TCR pathway
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Signaling events mediated by VEGFR1 and VEGFR2
|
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Insulin-mediated glucose transport
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N-cadherin signaling events
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Cellular roles of Anthrax toxin
|
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Regulation of Ras family activation
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Downstream signaling in naï
|
|
PathWhiz Pathway
|
Muscle/Heart Contraction
|
|
Reactome
|
Calmodulin induced events
|
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Platelet degranulation
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Translocation of GLUT4 to the plasma membrane
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Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
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DARPP-32 events
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eNOS activation
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Inactivation, recovery and regulation of the phototransduction cascade
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FCERI mediated Ca+2 mobilization
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Ca2+ pathway
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CREB phosphorylation through the activation of CaMKII
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Ras activation uopn Ca2+ infux through NMDA receptor
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Smooth Muscle Contraction
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VEGFR2 mediated vascular permeability
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VEGFR2 mediated cell proliferation
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RHO GTPases activate IQGAPs
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RAF/MAP kinase cascade
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Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
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WikiPathways
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Translocation of GLUT4 to the Plasma Membrane
|
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Visual phototransduction
|
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Fc epsilon receptor (FCERI) signaling
|
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Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
|
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Signaling by the B Cell Receptor (BCR)
|
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Inositol phosphate metabolism
|
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DAG and IP3 signaling
|
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Opioid Signalling
|
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Muscle contraction
|
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Metabolism of nitric oxide
|
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Metabolism of carbohydrates
|
| References |
| REF 1 | How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. |
|---|
