Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03SRV
|
||||
| Former ID |
DNC006993
|
||||
| Drug Name |
JWH-292
|
||||
| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C27H27NO2
|
||||
| Canonical SMILES |
CCCCCN1C=C(C=C1C2=CC=CC=C2OC)C(=O)C3=CC=CC4=CC=CC=C43
|
||||
| InChI |
1S/C27H27NO2/c1-3-4-9-17-28-19-21(18-25(28)24-14-7-8-16-26(24)30-2)27(29)23-15-10-12-20-11-5-6-13-22(20)23/h5-8,10-16,18-19H,3-4,9,17H2,1-2H3
|
||||
| InChIKey |
RWYPPHVLXFTKAG-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 1 | Target Info | Inhibitor | [1] | |
| Cannabinoid receptor 2 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors) | |||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2006 Oct 15;16(20):5432-5. Epub 2006 Aug 4.1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. | ||||
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