Drug Information
Drug General Information | |||||
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Drug ID |
D04BNM
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Former ID |
DNC014861
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Drug Name |
5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C12H12Cl2N2O4
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InChI |
InChI=1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1
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InChIKey |
XHSQDZXAVJRBMX-DDHJBXDOSA-N
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PubChem Compound ID | |||||
PubChem Substance ID |
598569, 8153647, 14923748, 24278361, 26683823, 29224921, 46511870, 47720224, 49882784, 53787056, 56463021, 57323027, 57654983, 71822673, 78194938, 87557378, 99350818, 99350819, 99444944, 103511359, 104310551, 124801296, 129690503, 134352066, 134971503, 137142262, 137923479, 139928731, 160969510, 164839842, 170482643, 170483349, 170483350, 178101868, 179236245, 184531847, 226443807, 241093254, 251963177, 252465579
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Target and Pathway | |||||
Target(s) | Casein kinase II, alpha chain | Target Info | Inhibitor | [2] | |
KEGG Pathway | Ribosome biogenesis in eukaryotes | ||||
NF-kappa B signaling pathway | |||||
Wnt signaling pathway | |||||
Adherens junction | |||||
Tight junction | |||||
Measles | |||||
Herpes simplex infection | |||||
Epstein-Barr virus infection | |||||
NetPath Pathway | FSH Signaling Pathway | ||||
Pathway Interaction Database | BCR signaling pathway | ||||
Atypical NF-kappaB pathway | |||||
DNA-PK pathway in nonhomologous end joining | |||||
Presenilin action in Notch and Wnt signaling | |||||
Role of Calcineurin-dependent NFAT signaling in lymphocytes | |||||
E-cadherin signaling in the nascent adherens junction | |||||
Lissencephaly gene (LIS1) in neuronal migration and development | |||||
PDGFR-alpha signaling pathway | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
Alpha-synuclein signaling | |||||
Reactome | Condensation of Prometaphase Chromosomes | ||||
WikiPathways | Mitotic Prometaphase | ||||
BDNF signaling pathway | |||||
TNF alpha Signaling Pathway | |||||
L1CAM interactions | |||||
References | |||||
REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5178). | ||||
REF 2 | Bioorg Med Chem Lett. 2009 Jun 1;19(11):2920-3. Epub 2009 Apr 22.Structural insight into human CK2alpha in complex with the potent inhibitor ellagic acid. | ||||
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