Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D05COG
|
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| Former ID |
DIB013764
|
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| Drug Name |
DU-1777
|
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| Drug Type |
Small molecular drug
|
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| Indication | Hypertension [ICD9: 401; ICD10:I10-I16] | Terminated | [1] | ||
| Company |
Dainippon Pharmaceutical Co Ltd
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C26H37N5O7
|
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| Canonical SMILES |
N1([C@@H](C[C@H]2[C@@H]1CCCC2)C(=O)O)C(=O)CC[C@@H](NC(=<br />O)[C@@H](NC(=O)c1cnccc1)CCCCN)C(=O)O
|
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| CAS Number |
CAS 116662-73-8
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Angiotensin-converting enzyme | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Renin-angiotensin system | ||||
| Chagas disease (American trypanosomiasis) | |||||
| Hypertrophic cardiomyopathy (HCM) | |||||
| PathWhiz Pathway | Angiotensin Metabolism | ||||
| Reactome | Metabolism of Angiotensinogen to Angiotensins | ||||
| WikiPathways | ACE Inhibitor Pathway | ||||
| Metabolism of Angiotensinogen to Angiotensins | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002041) | ||||
| REF 2 | Antihypertensive properties of a new long-acting angiotensin converting enzyme inhibitor in renin-dependent and independent hypertensive models. Arzneimittelforschung. 1995 Aug;45(8):853-8. | ||||
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