| Drug General Information |
| Drug ID |
D07LCW
|
| Former ID |
DNC012682
|
| Drug Name |
5-Azidomethyl-3-pyrrol-1-yl-oxazolidin-2-one
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C8H9N5O2
|
| Canonical SMILES |
C1C(OC(=O)N1N2C=CC=C2)CN=[N+]=[N-]
|
| InChI |
1S/C8H9N5O2/c9-11-10-5-7-6-13(8(14)15-7)12-3-1-2-4-12/h1-4,7H,5-6H2/t7-/m1/s1
|
| InChIKey |
RJURJCGAHMMGOY-SSDOTTSWSA-N
|
| PubChem Compound ID |
|
| Target and Pathway |
| Target(s) |
Amine oxidase [flavin-containing] A |
Target Info |
Inhibitor |
[1]
|
|---|
|
BioCyc Pathway
|
Superpathway of tryptophan utilization
|
|
Dopamine degradation
|
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Putrescine degradation III
|
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Noradrenaline and adrenaline degradation
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Serotonin degradation
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Superpathway of melatonin degradation
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Melatonin degradation II
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KEGG Pathway
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Glycine, serine and threonine metabolism
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Arginine and proline metabolism
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Histidine metabolism
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Tyrosine metabolism
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Phenylalanine metabolism
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Tryptophan metabolism
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Drug metabolism - cytochrome P450
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Metabolic pathways
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Serotonergic synapse
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Dopaminergic synapse
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Cocaine addiction
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Amphetamine addiction
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Alcoholism
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NetPath Pathway
|
IL4 Signaling Pathway
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PANTHER Pathway
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Adrenaline and noradrenaline biosynthesis
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5-Hydroxytryptamine degredation
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Dopamine receptor mediated signaling pathway
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PathWhiz Pathway
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Histidine Metabolism
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Tyrosine Metabolism
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Glycine and Serine Metabolism
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Reactome
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Norepinephrine Neurotransmitter Release Cycle
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WikiPathways
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SIDS Susceptibility Pathways
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Biogenic Amine Synthesis
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Oxidative Stress
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Dopamine metabolism
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Phase 1 - Functionalization of compounds
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Neurotransmitter Release Cycle
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Neurotransmitter Clearance In The Synaptic Cleft
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Serotonin Transporter Activity
|
| References |
| REF 1 | J Med Chem. 2002 Mar 14;45(6):1180-3.3-(1H-Pyrrol-1-yl)-2-oxazolidinones as reversible, highly potent, and selective inhibitors of monoamine oxidase type A. |
|---|
