Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07VCG
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| Former ID |
DIB003219
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| Drug Name |
Anti-VEGFR 3 mab
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| Synonyms |
Anti-VEGFR 3 mAb (undisclosed indication); Anti-VEGFR 3 mAb (undisclosed indication), PharmAbcine; Vascular endothelial growth factor receptor 3 inhibitor (mAb, undisclosed indication), PharmAbcine
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| Drug Type |
Monoclonal antibody
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| Indication | Discovery agent | Investigative | [1] | ||
| Company |
PharmAbcine
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| Target and Pathway | |||||
| Target(s) | Vascular endothelial growth factor receptor 3 | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| Cytokine-cytokine receptor interaction | |||||
| PI3K-Akt signaling pathway | |||||
| Focal adhesion | |||||
| NetPath Pathway | TNFalpha Signaling Pathway | ||||
| Pathway Interaction Database | VEGF and VEGFR signaling network | ||||
| VEGFR3 signaling in lymphatic endothelium | |||||
| Reactome | VEGF binds to VEGFR leading to receptor dimerization | ||||
| WikiPathways | Signaling by VEGF | ||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1814). | ||||
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