Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0B8AN
|
||||
| Former ID |
DNC006975
|
||||
| Drug Name |
JWH-347
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C30H27NO
|
||||
| Canonical SMILES |
CCCCCN1C=C(C=C1C2=CC3=CC=CC=C3C=C2)C(=O)C4=CC=CC5=CC=CC<br />=C54
|
||||
| InChI |
1S/C30H27NO/c1-2-3-8-18-31-21-26(30(32)28-15-9-13-23-11-6-7-14-27(23)28)20-29(31)25-17-16-22-10-4-5-12-24(22)19-25/h4-7,9-17,19-21H,2-3,8,18H2,1H3
|
||||
| InChIKey |
WYOWIOBJNTYRNN-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 1 | Target Info | Inhibitor | [1] | |
| Cannabinoid receptor 2 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signalinghsa04080:Neuroactive ligand-receptor interaction | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors) | |||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, OtherWP455:GPCRs, Class A Rhodopsin-like | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2006 Oct 15;16(20):5432-5. Epub 2006 Aug 4.1-Alkyl-2-aryl-4-(1-naphthoyl)pyrroles: new high affinity ligands for the cannabinoid CB1 and CB2 receptors. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.