Drug General Information
Drug ID	D0J4GG
Drug Name	LF-160335
Indication	Unspecified		Investigative	[1572605]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	B2 bradykinin receptor	Target Info	Modulator	[1572605]
KEGG Pathway	Calcium signaling pathway
	cGMP-PKG signaling pathway
	Sphingolipid signaling pathway
	Neuroactive ligand-receptor interaction
	Complement and coagulation cascades
	Inflammatory mediator regulation of TRP channels
	Regulation of actin cytoskeleton
	Endocrine and other factor-regulated calcium reabsorption
	Chagas disease (American trypanosomiasis)
	Pathways in cancer
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Pathway Interaction Database	Direct p53 effectors
	Validated transcriptional targets of deltaNp63 isoforms
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	G alpha (i) signalling events
WikiPathways	ACE Inhibitor Pathway
	Regulation of Actin Cytoskeleton
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Nifedipine Activity
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 1572605	The ChEMBL database in 2017.
Ref 1572605	The ChEMBL database in 2017.

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