Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0J7MM
|
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| Former ID |
DNC006949
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| Drug Name |
ADS-103316
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C22H24N4O3
|
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| Canonical SMILES |
CC1=NC(=NC2=C1C=C(C=C2)NC(=O)COC3=CC=C(C=C3)OC)N4CCCC4
|
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| InChI |
1S/C22H24N4O3/c1-15-19-13-16(5-10-20(19)25-22(23-15)26-11-3-4-12-26)24-21(27)14-29-18-8-6-17(28-2)7-9-18/h5-10,13H,3-4,11-12,14H2,1-2H3,(H,24,27)
|
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| InChIKey |
YXNSFDJSYOVION-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Melanin-concentrating hormone receptor 1 | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | ||||
| Reactome | Peptide ligand-binding receptors | ||||
| G alpha (q) signalling events | |||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists. | ||||
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