| Drug General Information |
| Drug ID |
D0L2KO
|
| Former ID |
DNC003875
|
| Drug Name |
Azaphenylalanine derivative
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Target and Pathway |
| Target(s) |
Coagulation factor Xa |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
|
Complement and coagulation cascades
|
|
PANTHER Pathway
|
Blood coagulation
|
|
Pathway Interaction Database
|
Beta2 integrin cell surface interactions
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PathWhiz Pathway
|
Coagulation
|
|
Reactome
|
Extrinsic Pathway of Fibrin Clot Formation
|
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Intrinsic Pathway of Fibrin Clot Formation
|
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Common Pathway of Fibrin Clot Formation
|
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Gamma-carboxylation of protein precursors
|
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Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
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Removal of aminoterminal propeptides from gamma-carboxylated proteins
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WikiPathways
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Complement and Coagulation Cascades
|
|
Human Complement System
|
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PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
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Blood Clotting Cascade
|
|
Formation of Fibrin Clot (Clotting Cascade)
|
| References |
| REF 1 | Bioorg Med Chem Lett. 2004 Mar 22;14(6):1563-7.Thrombin inhibitors built on an azaphenylalanine scaffold. |
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