Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M2GI
|
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| Former ID |
DIB016636
|
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| Drug Name |
CI-1002
|
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| Synonyms |
PD-142676
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| Indication | Alzheimer disease [ICD9: 331; ICD10:G30] | Terminated | [1] | ||
| Company |
Parke-Davis & Co
|
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| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
N1=C2N(Cc3c1cc(cc3Cl)Cl)CCCCC2
|
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| CAS Number |
CAS 149028-28-4
|
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| Target and Pathway | |||||
| Target(s) | Acetylcholinesterase | Target Info | Modulator | [1] | |
| KEGG Pathway | Glycerophospholipid metabolism | ||||
| Cholinergic synapse | |||||
| PANTHER Pathway | Muscarinic acetylcholine receptor 1 and 3 signaling pathway | ||||
| Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||||
| Nicotinic acetylcholine receptor signaling pathway | |||||
| Pathway Interaction Database | ATF-2 transcription factor network | ||||
| PathWhiz Pathway | Phospholipid Biosynthesis | ||||
| WikiPathways | Monoamine Transport | ||||
| Biogenic Amine Synthesis | |||||
| Acetylcholine Synthesis | |||||
| Integrated Pancreatic Cancer Pathway | |||||
| References | |||||
| REF 1 | PD 142676 (CI 1002), a novel anticholinesterase and muscarinic antagonist. Mol Neurobiol. 1994 Aug-Dec;9(1-3):93-106. | ||||
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