| Drug General Information |
| Drug ID |
D0MF5Y
|
| Former ID |
DNC003270
|
| Drug Name |
3,7,3',4'-TETRAHYDROXYFLAVONE
|
| Drug Type |
Small molecular drug
|
| Indication |
Discovery agent
|
Investigative |
[1]
|
|---|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C15H10O6
|
| Canonical SMILES |
C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O
|
| InChI |
1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
|
| InChIKey |
XHEFDIBZLJXQHF-UHFFFAOYSA-N
|
| PubChem Compound ID |
|
| PubChem Substance ID |
12227, 476876, 507096, 598776, 854619, 877431, 3133267, 7584531, 7887589, 8137407, 8616674, 10318997, 11108248, 11113262, 11113263, 11341731, 11361914, 11364090, 11366652, 11369214, 11372551, 11374538, 11377376, 11408257, 11446655, 11484855, 11487316, 11488976, 11491351, 11492884, 11495010, 11537677, 12015309, 14922300, 22389243, 26612353, 26680015, 26697264, 26749675, 26753766, 29204137, 39290396, 46393572, 47960466, 48035861, 48421823, 49833373, 49970085, 50123013, 52761154
|
| Target and Pathway |
| Target(s) |
Cell division protein kinase 6 |
Target Info |
Inhibitor |
[1]
|
|---|
|
KEGG Pathway
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Cell cycle
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|
p53 signaling pathway
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PI3K-Akt signaling pathway
|
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Hepatitis B
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Measles
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Pathways in cancer
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Viral carcinogenesis
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MicroRNAs in cancer
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Pancreatic cancer
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Glioma
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Melanoma
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Chronic myeloid leukemia
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Small cell lung cancer
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Non-small cell lung cancer
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NetPath Pathway
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TGF_beta_Receptor Signaling Pathway
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Pathway Interaction Database
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p73 transcription factor network
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Coregulation of Androgen receptor activity
|
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C-MYB transcription factor network
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IL2 signaling events mediated by STAT5
|
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Regulation of retinoblastoma protein
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Reactome
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Oxidative Stress Induced Senescence
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Senescence-Associated Secretory Phenotype (SASP)
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Oncogene Induced Senescence
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Cyclin D associated events in G1
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WikiPathways
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DNA Damage Response
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G1 to S cell cycle control
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Wnt Signaling Pathway Netpath
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Retinoblastoma (RB) in Cancer
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Signaling Pathways in Glioblastoma
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Metastatic brain tumor
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miR-targeted genes in muscle cell - TarBase
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miR-targeted genes in lymphocytes - TarBase
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miR-targeted genes in leukocytes - TarBase
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miR-targeted genes in epithelium - TarBase
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Mitotic G1-G1/S phases
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Cell Cycle
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miRNAs involved in DNA damage response
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miRNA Regulation of DNA Damage Response
|
| References |
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
|---|
