Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0N0UY
|
||||
| Former ID |
DCL000458
|
||||
| Drug Name |
AZD1704
|
||||
| Indication | Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89] | Discontinued in Phase 1 | [1] | ||
| Company |
AstraZeneca
|
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| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 1 | Target Info | Antagonist | [2] | |
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signaling | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028889) | ||||
| REF 2 | Clinical pipeline report, company report or official report of AstraZeneca (2009). | ||||
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