Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0NF7S
|
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| Former ID |
DIB012032
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| Drug Name |
R-59494
|
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| Drug Type |
Small molecular drug
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| Indication | Ischemia [ICD9: 459.89; ICD10:I99.8] | Terminated | [1] | ||
| Company |
Janssen Pharmaceutica NV
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C22H23N3OS
|
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| Canonical SMILES |
c1(nc2c(s1)cccc2)N(C1CN(CC1)CCCCOc1ccccc1)C
|
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| CAS Number |
CAS 104588-44-5
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium channel | Target Info | Modulator | [2] | |
| KEGG Pathway | Dopaminergic synapse | ||||
| Reactome | Interaction between L1 and Ankyrins | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002300) | ||||
| REF 2 | Veratridine activates a silent sodium channel in rat isolated aorta. Eur J Pharmacol. 1992 Aug 25;219(2):253-9. | ||||
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