Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0T7XN
|
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| Former ID |
DNC000586
|
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| Drug Name |
E-2070
|
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| Drug Type |
Small molecular drug
|
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| Indication | Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] | Terminated | [1] | ||
| Therapeutic Class |
Analgesics
|
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| Company |
Eisai Inc.
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C7H12Cl3O4P
|
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| Canonical SMILES |
CCCOP(=O)(OCCCl)OC=C(Cl)Cl
|
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| InChI |
1S/C7H12Cl3O4P/c1-2-4-12-15(11,13-5-3-8)14-6-7(9)10/h6H,2-5H2,1H3
|
||||
| InChIKey |
UVHUICINDSEUQN-UHFFFAOYSA-N
|
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| CAS Number |
CAS 64050-66-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium channel | Target Info | Blocker | [2] | |
| KEGG Pathway | Dopaminergic synapse | ||||
| Reactome | Interaction between L1 and Ankyrins | ||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019940) | ||||
| REF 2 | Emerging therapies for neuropathic pain. Expert Opin Emerg Drugs. 2005 Feb;10(1):95-108. | ||||
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