Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0V4FW
|
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| Former ID |
DNC010225
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| Drug Name |
{2-[3-(Phenylsulfonyl)-1H-indol-4-yl]ethyl}amine
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C16H16N2O2S
|
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| Canonical SMILES |
C1=CC=C(C=C1)S(=O)(=O)C2=CNC3=CC=CC(=C32)CCN
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| InChI |
1S/C16H16N2O2S/c17-10-9-12-5-4-8-14-16(12)15(11-18-14)21(19,20)13-6-2-1-3-7-13/h1-8,11,18H,9-10,17H2
|
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| InChIKey |
RSVUNKKDIROCQS-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Sodium-dependent noradrenaline transporter | Target Info | Inhibitor | [1] | |
| PANTHER Pathway | Adrenaline and noradrenaline biosynthesis | ||||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | ||||
| WikiPathways | Monoamine Transport | ||||
| NRF2 pathway | |||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | |||||
| References | |||||
| REF 1 | Bioorg Med Chem. 2009 Nov 15;17(22):7802-15. Epub 2009 Sep 18.Dual acting norepinephrine reuptake inhibitors and 5-HT(2A) receptor antagonists: Identification, synthesis and activity of novel 4-aminoethyl-3-(phenylsulfonyl)-1H-indoles. | ||||
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