Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0X6PG
|
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| Former ID |
DIB012332
|
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| Drug Name |
LY-274614
|
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| Drug Type |
Small molecular drug
|
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| Indication | Dementia [ICD9: 290-294; ICD10:F01-F07] | Terminated | [1] | ||
| Company |
Eli Lilly & Co
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C11H20NO5P
|
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| Canonical SMILES |
P(=O)(C[C@@H]1C[C@@H]2C[C@H](NC[C@@H]2CC1)C(=O)O)(O)O
|
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| CAS Number |
CAS 136109-04-1
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | NMDA receptor | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001393) | ||||
| REF 2 | The NMDA receptor antagonists, LY274614 and MK-801, and the nitric oxide synthase inhibitor, NG-nitro-L-arginine, attenuate analgesic tolerance to the mu-opioid morphine but not to kappa opioids. Pain. 1994 Jan;56(1):69-75. | ||||
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