| Drug General Information |
| Drug ID |
D0XB8R
|
| Former ID |
DAP001506
|
| Drug Name |
Pravigard
|
| Drug Type |
Small molecular drug
|
| Indication |
Myocardial infarction; Cerebrovascular ischaemia [ICD9: 410, 434.91; ICD10:I21, I22, I61-I63]
|
Approved |
[1]
|
|---|
| Company |
Bristol-Myers Squibb
|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C9H8O4
|
| Canonical SMILES |
CC(=O)OC1=CC=CC=C1C(=O)O
|
| InChI |
1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
|
| InChIKey |
BSYNRYMUTXBXSQ-UHFFFAOYSA-N
|
| CAS Number |
CAS 98201-60-6
|
| PubChem Compound ID |
|
| PubChem Substance ID |
4594, 87798, 476106, 602429, 829042, 832958, 840714, 3135921, 5261264, 7847177, 7885805, 7978731, 8143164, 8149208, 8151516, 10524572, 11110749, 11335730, 11360969, 11364139, 11364685, 11366701, 11367247, 11369263, 11369809, 11372248, 11372850, 11373537, 11375409, 11377425, 11377972, 11406615, 11461941, 11485574, 11489715, 11491110, 11491914, 11495059, 15195166, 17389202, 17390036, 17404602, 24278218, 24714725, 24890623, 24890723, 24891140, 26611613, 26679412, 26717767
|
| Target and Pathway |
| Target(s) |
3-hydroxy-3-methylglutaryl-coenzyme A reductase |
Target Info |
Inhibitor |
[1]
|
|---|
| Cyclooxygenase |
Target Info |
Inhibitor |
[1]
|
|
BioCyc Pathway
|
Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate)
|
|
Superpathway of cholesterol biosynthesis
|
|
Mevalonate pathway
|
|
KEGG Pathway
|
Terpenoid backbone biosynthesis
|
|
Metabolic pathways
|
|
Biosynthesis of antibiotics
|
|
AMPK signaling pathway
|
|
Bile secretion
|
|
NetPath Pathway
|
IL5 Signaling Pathway
|
|
TGF_beta_Receptor Signaling Pathway
|
|
TSH Signaling Pathway
|
|
PANTHER Pathway
|
Cholesterol biosynthesis
|
|
PathWhiz Pathway
|
Steroid Biosynthesis
|
|
WikiPathways
|
Statin Pathway
|
|
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
|
|
Activation of Gene Expression by SREBP (SREBF)
|
|
SREBF and miR33 in cholesterol and lipid homeostasis
|
|
Integrated Breast Cancer Pathway
|
|
SREBP signalling
|
|
Cholesterol Biosynthesis
|
| References |
| REF 1 | Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90. |
|---|
