Drug Information
Drug General Information | |||||
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Drug ID |
D0Y8CU
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Former ID |
DNC014778
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Drug Name |
5,6,8-trichloroquinoline-4-one-3-carboxylic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C10H4Cl3NO3
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Canonical SMILES |
C1=C(C2=C(C(=C1Cl)Cl)C(=O)C(=CN2)C(=O)O)Cl
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InChI |
1S/C10H4Cl3NO3/c11-4-1-5(12)8-6(7(4)13)9(15)3(2-14-8)10(16)17/h1-2H,(H,14,15)(H,16,17)
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InChIKey |
DIMMLVONVUPWHB-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Casein kinase II, alpha chain | Target Info | Inhibitor | [1] | |
KEGG Pathway | Ribosome biogenesis in eukaryotes | ||||
NF-kappa B signaling pathway | |||||
Wnt signaling pathway | |||||
Adherens junction | |||||
Tight junction | |||||
Measles | |||||
Herpes simplex infection | |||||
Epstein-Barr virus infection | |||||
NetPath Pathway | FSH Signaling Pathway | ||||
Pathway Interaction Database | BCR signaling pathway | ||||
Atypical NF-kappaB pathway | |||||
DNA-PK pathway in nonhomologous end joining | |||||
Presenilin action in Notch and Wnt signaling | |||||
Role of Calcineurin-dependent NFAT signaling in lymphocytes | |||||
E-cadherin signaling in the nascent adherens junction | |||||
Lissencephaly gene (LIS1) in neuronal migration and development | |||||
PDGFR-alpha signaling pathway | |||||
Signaling mediated by p38-alpha and p38-beta | |||||
Alpha-synuclein signaling | |||||
Reactome | Condensation of Prometaphase Chromosomes | ||||
WikiPathways | Mitotic Prometaphase | ||||
BDNF signaling pathway | |||||
TNF alpha Signaling Pathway | |||||
L1CAM interactions | |||||
References | |||||
REF 1 | J Med Chem. 2006 Nov 2;49(22):6443-50.Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2. | ||||
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