Drug Information

Drug General Information
Drug ID
D06EHE
Former ID
DNC003217
Drug Name
6-Hydroxy-1,6-Dihydro Purine Nucleoside
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
Download
2D MOL

3D MOL
Formula
C10H15N4O5+
Canonical SMILES
C1=NC(C2=C(N1)[N+](=CN2)C3C(C(C(O3)CO)O)O)O
InChI
1S/C10H14N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,9-10,15-18H,1H2,(H,11,12)/p+1/t4-,6-,7-,9+,10-/m1/s1
InChIKey
WGRXVKRHIMUTPD-YOHZANMFSA-O
PubChem Compound ID
5289205
PubChem Substance ID
7890045, 39321446, 75176665, 113873792
Target and Pathway
Target(s) Adenosine deaminase Target Info Inhibitor [551393]
BioCyc Pathway Purine nucleotides degradation
Purine deoxyribonucleosides degradation
Purine ribonucleosides degradation to ribose-1-phosphate
Adenosine nucleotides degradation
Superpathway of purine nucleotide salvage
Adenine and adenosine salvage III
KEGG Pathway Purine metabolism
Metabolic pathways
Primary immunodeficiency
NetPath Pathway TCR Signaling Pathway
IL2 Signaling Pathway
PANTHER Pathway Adenine and hypoxanthine salvage pathway
Pathway Interaction Database p73 transcription factor network
C-MYB transcription factor network
Validated transcriptional targets of deltaNp63 isoforms
Validated transcriptional targets of TAp63 isoforms
PathWhiz Pathway Purine Metabolism
Reactome Purine salvage
WikiPathways Metabolism of nucleotides
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.