Drug Information
Drug General Information | |||||
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Drug ID |
D0B0LU
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Former ID |
DNC009295
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Drug Name |
[2-(Imidazol-2-yl-thio)ethyl]-bisphosphonic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C5H10N2O6P2S
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Canonical SMILES |
C1=CN=C(N1)SCC(P(=O)(O)O)P(=O)(O)O
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InChI |
1S/C5H10N2O6P2S/c8-14(9,10)4(15(11,12)13)3-16-5-6-1-2-7-5/h1-2,4H,3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)
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InChIKey |
KVMQBCIVXMEYRO-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Farnesyl pyrophosphatesynthetase | Target Info | Inhibitor | [1] | |
KEGG Pathway | Terpenoid backbone biosynthesis | ||||
Metabolic pathways | |||||
Biosynthesis of antibiotics | |||||
Influenza A | |||||
HTLV-I infection | |||||
PathWhiz Pathway | Steroid Biosynthesis | ||||
Reactome | Cholesterol biosynthesis | ||||
Activation of gene expression by SREBF (SREBP) | |||||
WikiPathways | Activation of Gene Expression by SREBP (SREBF) | ||||
SREBP signalling | |||||
Cholesterol Biosynthesis | |||||
References | |||||
REF 1 | J Med Chem. 2008 Nov 13;51(21):6800-7. Epub 2008 Oct 21.Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism. | ||||
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