Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0B0LU
|
||||
| Former ID |
DNC009295
|
||||
| Drug Name |
[2-(Imidazol-2-yl-thio)ethyl]-bisphosphonic acid
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C5H10N2O6P2S
|
||||
| Canonical SMILES |
C1=CN=C(N1)SCC(P(=O)(O)O)P(=O)(O)O
|
||||
| InChI |
1S/C5H10N2O6P2S/c8-14(9,10)4(15(11,12)13)3-16-5-6-1-2-7-5/h1-2,4H,3H2,(H,6,7)(H2,8,9,10)(H2,11,12,13)
|
||||
| InChIKey |
KVMQBCIVXMEYRO-UHFFFAOYSA-N
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Farnesyl pyrophosphatesynthetase | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Terpenoid backbone biosynthesis | ||||
| Metabolic pathways | |||||
| Biosynthesis of antibiotics | |||||
| Influenza A | |||||
| HTLV-I infection | |||||
| PathWhiz Pathway | Steroid Biosynthesis | ||||
| Reactome | Cholesterol biosynthesis | ||||
| Activation of gene expression by SREBF (SREBP) | |||||
| WikiPathways | Activation of Gene Expression by SREBP (SREBF) | ||||
| SREBP signalling | |||||
| Cholesterol Biosynthesis | |||||
| References | |||||
| REF 1 | J Med Chem. 2008 Nov 13;51(21):6800-7. Epub 2008 Oct 21.Design, synthesis, and biological evaluation of novel aminobisphosphonates possessing an in vivo antitumor activity through a gammadelta-T lymphocytes-mediated activation mechanism. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.