Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00QUN
|
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| Former ID |
DNC014027
|
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| Drug Name |
Isopropyl 4-nitrophenyl dodecylphosphonate
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C21H36NO5P
|
||||
| Canonical SMILES |
CCCCCCCCCCCCP(=O)(OC1=CC=C(C=C1)[N+](=O)[O-])OC(C)C
|
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| InChI |
1S/C21H36NO5P/c1-4-5-6-7-8-9-10-11-12-13-18-28(25,26-19(2)3)27-21-16-14-20(15-17-21)22(23)24/h14-17,19H,4-13,18H2,1-3H3
|
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| InChIKey |
VZXZHBVWVCMVBS-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 1 | Target Info | Inhibitor | [1] | |
| Fatty-acid amide hydrolase | Target Info | Inhibitor | [1] | ||
| BioCyc Pathway | Anandamide degradation | ||||
| KEGG Pathway | Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signalinghsa04723:Retrograde endocannabinoid signaling | |||||
| PANTHER Pathway | Endogenous cannabinoid signalingP05728:Anandamide degradation | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| BDNF signaling pathway | |||||
| GPCR ligand binding | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2008 Nov 15;18(22):5875-8. Epub 2008 Aug 6.Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels. | ||||
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