Drug Information
Drug General Information | |||||
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Drug ID |
D0L1RM
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Former ID |
DNC013544
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Drug Name |
1-[(prop-1-ylamino)ethyl]-1,1-bisphosphonic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent | Investigative | [1] | ||
Structure |
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Download2D MOL |
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Formula |
C5H15NO6P2
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Canonical SMILES |
CCCNCC(P(=O)(O)O)P(=O)(O)O
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InChI |
1S/C5H15NO6P2/c1-2-3-6-4-5(13(7,8)9)14(10,11)12/h5-6H,2-4H2,1H3,(H2,7,8,9)(H2,10,11,12)
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InChIKey |
YFFJUBPLIKXHAO-UHFFFAOYSA-N
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PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | Farnesyl pyrophosphatesynthetase | Target Info | Inhibitor | [1] | |
KEGG Pathway | Terpenoid backbone biosynthesis | ||||
Metabolic pathways | |||||
Biosynthesis of antibiotics | |||||
Influenza A | |||||
HTLV-I infection | |||||
PathWhiz Pathway | Steroid Biosynthesis | ||||
Reactome | Cholesterol biosynthesis | ||||
Activation of gene expression by SREBF (SREBP) | |||||
WikiPathways | Activation of Gene Expression by SREBP (SREBF) | ||||
SREBP signalling | |||||
Cholesterol Biosynthesis | |||||
References | |||||
REF 1 | Bioorg Med Chem. 2008 Mar 15;16(6):3283-90. Epub 2007 Dec 10.Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. | ||||
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