Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D00FKJ
|
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| Former ID |
DNC009443
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| Drug Name |
(1S,2R)-N-Oleoylcyclopropanolamide
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Canonical SMILES |
CCCCCCCCCCCCCCCC(=O)NC1CC1O
|
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| InChI |
1S/C19H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(22)20-17-16-18(17)21/h17-18,21H,2-16H2,1H3,(H,20,22)/t17-,18+/m1/s1
|
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| InChIKey |
LIBNBUULGCFJNR-MSOLQXFVSA-N
|
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| Target and Pathway | |||||
| Target(s) | Cannabinoid receptor 2 | Target Info | Inhibitor | [1] | |
| Cannabinoid receptor 1 | Target Info | Inhibitor | [1] | ||
| KEGG Pathway | Neuroactive ligand-receptor interactionhsa04015:Rap1 signaling pathway | ||||
| Neuroactive ligand-receptor interaction | |||||
| Retrograde endocannabinoid signaling | |||||
| PANTHER Pathway | Endogenous cannabinoid signaling | ||||
| Pathway Interaction Database | N-cadherin signaling events | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | ||||
| G alpha (i) signalling eventsR-HSA-373076:Class A/1 (Rhodopsin-like receptors) | |||||
| G alpha (i) signalling events | |||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | ||||
| Small Ligand GPCRs | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like | |||||
| BDNF signaling pathway | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| REF 1 | J Med Chem. 2009 May 14;52(9):3001-9.Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes. | ||||
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