Drug Information
Drug General Information | |||||
---|---|---|---|---|---|
Drug ID |
D0C4NA
|
||||
Former ID |
DNC010382
|
||||
Drug Name |
NSC-154957
|
||||
Drug Type |
Small molecular drug
|
||||
Indication | Discovery agent | Investigative | [1] | ||
Structure |
![]() |
Download2D MOL |
|||
Formula |
C17H17NO3S
|
||||
Canonical SMILES |
C1=CC=C(C=C1)C(C2=CC=CC=C2)SCC(C(=O)O)NC=O
|
||||
InChI |
1S/C17H17NO3S/c19-12-18-15(17(20)21)11-22-16(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,12,15-16H,11H2,(H,18,19)(H,20,21)
|
||||
InChIKey |
QUWUQXPHWCHJIS-UHFFFAOYSA-N
|
||||
PubChem Compound ID | |||||
Target and Pathway | |||||
Target(s) | DNA (cytosine-5)-methyltransferase 3B | Target Info | Inhibitor | [1] | |
DNA (cytosine-5)-methyltransferase | Target Info | Inhibitor | [1] | ||
KEGG Pathway | Cysteine and methionine metabolism | ||||
Metabolic pathways | |||||
MicroRNAs in cancer | |||||
Reactome | PRC2 methylates histones and DNA | ||||
NoRC negatively regulates rRNA expression | |||||
DNA methylation | |||||
WikiPathways | Mesodermal Commitment Pathway | ||||
Endoderm Differentiation | |||||
Trans-sulfuration and one carbon metabolism | |||||
One Carbon Metabolism | |||||
miR-targeted genes in lymphocytes - TarBase | |||||
References | |||||
REF 1 | Bioorg Med Chem. 2010 Jan 15;18(2):822-9. Epub 2009 Nov 27.Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.