Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D07BFF
|
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| Former ID |
DNC006241
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| Drug Name |
8-methyl-2-morpholino-7-phenyl-4H-chromen-4-one
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [1] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C20H19NO3
|
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| Canonical SMILES |
CC1=C(C=CC2=C1OC(=CC2=O)N3CCOCC3)C4=CC=CC=C4
|
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| InChI |
1S/C20H19NO3/c1-14-16(15-5-3-2-4-6-15)7-8-17-18(22)13-19(24-20(14)17)21-9-11-23-12-10-21/h2-8,13H,9-12H2,1H3
|
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| InChIKey |
ZMYPEBFYGCAKQT-UHFFFAOYSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | CGMP-inhibited 3',5'-cyclic phosphodiesterase A | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Purine metabolism | ||||
| cGMP-PKG signaling pathway | |||||
| cAMP signaling pathway | |||||
| Morphine addiction | |||||
| Reactome | cGMP effects | ||||
| G alpha (s) signalling events | |||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| References | |||||
| REF 1 | Bioorg Med Chem Lett. 2006 Feb 15;16(4):969-73. Epub 2005 Nov 15.Analysis of anti-PDE3 activity of 2-morpholinochromone derivatives reveals multiple mechanisms of anti-platelet activity. | ||||
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