Drug General Information |
Drug ID |
D03EOD
|
Former ID |
DNC004004
|
Drug Name |
4-[2,2-bis(4-hydroxyphenyl)-1-methylvinyl]phenol
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Drug Type |
Small molecular drug
|
Indication |
Discovery agent
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Investigative |
[1]
|
Structure |
|
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2D MOL
3D MOL
|
Formula |
C21H18O3
|
Canonical SMILES |
CC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)O)C3=CC=C(C=C3)O
|
InChI |
1S/C21H18O3/c1-14(15-2-8-18(22)9-3-15)21(16-4-10-19(23)11-5-16)17-6-12-20(24)13-7-17/h2-13,22-24H,1H3
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InChIKey |
FFGNPMKMQDXQJJ-UHFFFAOYSA-N
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PubChem Compound ID |
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Target and Pathway |
Target(s) |
Estrogen receptor beta |
Target Info |
Inhibitor |
[1]
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Estrogen receptor |
Target Info |
Inhibitor |
[1]
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KEGG Pathway
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Estrogen signaling pathway
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Prolactin signaling pathwayhsa04915:Estrogen signaling pathway
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Prolactin signaling pathway
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Thyroid hormone signaling pathway
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Endocrine and other factor-regulated calcium reabsorption
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Proteoglycans in cancer
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NetPath Pathway
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FSH Signaling Pathway
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EGFR1 Signaling Pathway
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RANKL Signaling Pathway
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Pathway Interaction Database
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Plasma membrane estrogen receptor signaling
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Validated nuclear estrogen receptor beta network
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Validated nuclear estrogen receptor alpha networksmad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling
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Signaling events mediated by HDAC Class II
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LKB1 signaling events
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Regulation of Telomerase
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ATF-2 transcription factor network
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AP-1 transcription factor network
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FOXM1 transcription factor network
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Validated nuclear estrogen receptor alpha network
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Signaling mediated by p38-alpha and p38-beta
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FOXA1 transcription factor network
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Reactome
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Nuclear Receptor transcription pathwayR-HSA-1251985:Nuclear signaling by ERBB4
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Nuclear Receptor transcription pathway
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WikiPathways
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SIDS Susceptibility Pathways
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Ovarian Infertility Genes
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Integrated Pancreatic Cancer Pathway
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Nuclear ReceptorsWP712:Estrogen signaling pathway
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Nuclear Receptors Meta-Pathway
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Estrogen Receptor Pathway
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Signaling by ERBB4
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JAK/STAT
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Leptin signaling pathway
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miR-targeted genes in muscle cell - TarBase
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Integrated Breast Cancer Pathway
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Nuclear Receptors
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References |
REF 1 | J Med Chem. 2003 Apr 10;46(8):1484-91.Antiestrogenically active 1,1,2-tris(4-hydroxyphenyl)alkenes without basic side chain: synthesis and biological activity. |